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  3. TAS1R2 - taste 1 receptor member 2 Gene

TAS1R2 - taste 1 receptor member 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：味觉 1 受体成员 2

种属: Homo sapiens

同用名: TR2; T1R2; GPR71

基因 ID: 80834 | 基因类型: protein coding

关于 TAS1R2

Cytogenetic location: 1p36.13 Genomic coordinates (GRCh38): 1:18,839,599-18,859,660 (from NCBI)

This gene has 1 transcript (splice variant), 359 orthologues and 4 paralogues. Low expression observed in reference dataset.

功能概要

有助于甜味受体活性。参与检测参与甜味感官知觉和胞质分裂正调节的化学刺激。甜味受体复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Contributes to sweet Taste Receptor activity. Involved in detection of chemical stimulus involved in sensory perception of sweet taste and positive regulation of cytokinesis. Part of sweet Taste Receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

TAS1R2 基因产物(1)

mRNA Protein Name
NM_152232.6 NP_689418.2 taste receptor type 1 member 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to sweet taste receptor activity IDA
IDA: 通过直接分析推断
16720576 GOA
contributes to taste receptor activity IDA
IDA: 通过直接分析推断
16720576 GOA
enables taste receptor activity IPI
IPI: 通过物理相互作用推断
11917125 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in detection of chemical stimulus involved in sensory perception of sweet taste IDA
IDA: 通过直接分析推断
16720576 GOA
involved in positive regulation of cytokinesis IMP
IMP: 通过突变表型推断
22888021 GOA
involved in sensory perception of sweet taste IDA
IDA: 通过直接分析推断
11917125 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of receptor complex IDA
IDA: 通过直接分析推断
23382219 GOA
part of sweet taste receptor complex IDA
IDA: 通过直接分析推断
16720576 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TAS1R2 蛋白结构

ANF_receptor

ANF_receptor: Receptor family ligand binding region (71 - 454)

NCD3G

NCD3G: Nine Cysteines Domain of family 3 GPCR (491 - 544)

7tm_3

7tm_3: 7 transmembrane sweet-taste receptor of 3 GCPR (575 - 815)

  • 0
  • 200
  • 400
  • 600
  • 839 a.a.
蛋白主名 其他名称

taste receptor type 1 member 2

G-protein coupled receptor 71

关联疾病

疾病名称 别名
Dental Caries

Dental Caries Extending Into Pulp

Dental Caries Of Smooth Surface

Dental Caries Pit And Fissure

Smooth Surface Dental Caries

Dental Decay

Carious Teeth

Dental Cavity

Saprodontia

Teeth Decayed

Tooth Caries

Tooth Decay
Renal Pelvis Transitional Cell Carcinoma

Urothelial Cell Carcinoma Of Renal Pelvis

Renal Pelvis Urothelial Carcinoma

Transitional Cell Carcinoma Of Renal Pelvis
Glucocorticoid Deficiency 1

Acth Resistance

Glucocorticoid Deficiency, Due To Acth Unresponsiveness

GCCD1

Familial Glucocorticoid Deficiency 1

Fgd1

Adrenal Unresponsiveness To Acth

Hereditary Unresponsiveness To Adrenocorticotropic Hormone

Isolated Glucocorticoid Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2084 Perillartine 99.80% 否
HY-RS14213 TAS1R2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TAS1R2 VGNC VGNC:35608
Macaca mulatta TAS1R2 VGNC VGNC:100154
Rattus norvegicus TAS1R2 RGD RGD:61894
Mus musculus TAS1R2 MGD MGI:1933546
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