SYMPK - symplekin scaffold protein Gene

中文名称：symplekin 支架蛋白

种属: Homo sapiens

同用名: SPK; SYM; Pta1

关于 SYMPK

功能概要

该基因编码一种核蛋白，该蛋白在多聚腺苷酸化的调节中发挥作用并促进基因表达。该蛋白质与聚腺苷酸化机制的成分形成高分子量复合物。它被认为是将调节因子募集到聚腺苷酸化复合体的支架。它还参与不进行聚腺苷酸化的组蛋白 mRNA 的 3' 端成熟。该蛋白质还定位于某些细胞类型中紧密连接的细胞质斑块。[RefSeq 提供，2008 年 7 月]

This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]