2. Gene
  3. SARNP - SAP domain containing ribonucleoprotein Gene

SARNP - SAP domain containing ribonucleoprotein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含核糖核蛋白的 SAP 结构域

种属: Homo sapiens

同用名: HCC1; THO1; CIP29; HSPC316

基因 ID: 84324 | 基因类型: protein coding

关于 SARNP

Cytogenetic location: 12q13.2 Genomic coordinates (GRCh38): 12:55,752,463-55,817,724 (from NCBI)

This gene has 6 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in testis (RPKM 27.2), endometrium (RPKM 26.0) and 25 other tissues.

功能概要

该基因编码一种蛋白质，该蛋白质会响应各种细胞因子而上调。编码的蛋白质可能在细胞周期进程中发挥作用。该基因与髓细胞/淋巴细胞白血病基因之间的易位导致嵌合蛋白的表达，与急性髓单核细胞白血病有关。 7 号和 8 号染色体上存在假基因。已经描述了选择性剪接的转录物变体。[RefSeq 提供，2009 年 2 月]

This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

SARNP 基因产物(1)

mRNA Protein Name
NM_033082.4 NP_149073.1 SAP domain-containing ribonucleoprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14667819 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mRNA export from nucleus IDA
IDA: 通过直接分析推断
20844015 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear speck IDA
IDA: 通过直接分析推断
20844015 GOA
part of transcription export complex IDA
IDA: 通过直接分析推断
20844015 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SARNP 蛋白结构

SAP

SAP: SAP domain (8 - 42)

  • 0
  • 100
  • 210 a.a.
蛋白主名 其他名称

SAP domain-containing ribonucleoprotein

cytokine induced protein 29 kDa

SARNP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SARNP P82979 DDX39A Homo sapiens O00148
Anti Tag CoIP
33961781
Intra SARNP P82979 DDX39A Homo sapiens O00148
Y2H Array
25416956
Intra SARNP P82979 DDX39A Homo sapiens O00148
Y2H Prey Pooling
25416956
Intra SARNP P82979 DDX39B Homo sapiens Q13838
Y2H Prey Pooling
32296183
Intra SARNP P82979 DDX39B Homo sapiens Q13838
Anti Tag CoIP
33961781
Intra SARNP P82979 DDX39B Homo sapiens Q13838
Validated Y2H
32296183
Intra SARNP P82979 DDX39B Homo sapiens Q13838
Y2H Array
32296183
Intra SARNP P82979 U2AF1 Homo sapiens Q01081
FRET
18559666
Intra SARNP P82979 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra SARNP P82979 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra SARNP P82979 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra SARNP P82979 U2AF2 Homo sapiens P26368
FRET
18559666
Intra SARNP P82979 U2AF2 Homo sapiens P26368
Anti Bait CoIP
18559666
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Acute Myelomonocytic Leukemia

Acute Myeloid Leukemia With Abnormal Bone Marrow Eosinophils Inv(16)(P13q22) Or T(16

16)(P13

Q22)

Aml M4

Ammol

Acute Myeloblastic Leukemia Type 4

Aml With Abnormal Bone Marrow Eosinophils Inv(16)(P13q22) Or T(16

16)(P13

Q22)

Aml-M4

Aml With Inv(16)(P13.1q22) Or T(16

16)(P13.1

Q22)

Cbfb-Myh11

Leukemia Myelomonocytic Acute

Leukemia, Myelomonocytic, Acute

Acute Myelomonocytic Leukaemia Without Mention Of Remission

Myelomonocytic Leukaemia Nos
Non-Gestational Choriocarcinoma

Choriocarcinoma, Non-Gestational
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 1

Eec Syndrome

Rudiger Syndrome 1

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 1

EEC1

Eec Syndrome 1

Eec Syndrome-1

Walker-Clodius Syndrome

Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Palate Syndrome

Eec

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome

Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

Ectrodactyly-Cleft Lip/Palate Syndrome

Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Cleft Palate

Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

Ectrodactyly, Ectodermal Dysplasia, Clefting Syndrome

Ectrodactyly-Cleft Lip-Palate Syndrome

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome
Superficial Urinary Bladder Cancer

Superficial Urinary Bladder Carcinoma

Carcinoma Of Urinary Bladder, Superficial
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12447 SARNP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SARNP RGD RGD:1305692
Canis familiaris SARNP VGNC VGNC:54543
Mus musculus SARNP MGD MGI:1913368
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