2. Gene
  3. Ppp1r9a - protein phosphatase 1, regulatory subunit 9A Gene

Ppp1r9a - protein phosphatase 1, regulatory subunit 9A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Neb1; p180; PP1bp175

基因 ID: 84685 | 基因类型: protein coding

关于 Ppp1r9a

功能概要

Enables several functions, including Enzyme binding activity; protein C-terminus binding activity; and transmembrane transporter binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of actin filament organization; and regulation of synapse organization. Acts upstream of or within neuron projection development. Located in several cellular components, including dendritic spine neck; growth cone lamellipodium; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic actin Cytoskeleton. Used to study transient cerebral ischemia. Biomarker of hepatocellular carcinoma. Orthologous to human PPP1R9A (protein Phosphatase 1 regulatory subunit 9A). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1r9a 基因产物(2)

mRNA Protein Name
NM_001401497.1 NP_001388426.1 neurabin-1 isoform 1
NM_053473.3 NP_445925.1 neurabin-1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase binding IDA
IDA: 通过直接分析推断
16525025 RGD
enables actin filament binding IDA
IDA: 通过直接分析推断
9362513 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9362513 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9653190 RGD
enables protein domain specific binding IDA
IDA: 通过直接分析推断
10514494 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
9653190 RGD
enables protein phosphatase 1 binding IDA
IDA: 通过直接分析推断
16899074 RGD
enables protein phosphatase 1 binding IPI
IPI: 通过物理相互作用推断
9282913 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
10504266 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
16025302 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to toxic substance IDA
IDA: 通过直接分析推断
12052877 RGD
involved in excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
15473970 RGD
involved in negative regulation of long-term synaptic potentiation IMP
IMP: 通过突变表型推断
16899074 RGD
involved in negative regulation of spontaneous neurotransmitter secretion IMP
IMP: 通过突变表型推断
16899074 RGD
involved in negative regulation of stress fiber assembly IMP
IMP: 通过突变表型推断
12052877 RGD
involved in neuron development IEP
IEP: 通过表达模式推断
9362513 RGD
acts upstream of or within neuron projection development IDA
IDA: 通过直接分析推断
16525025 RGD
involved in positive regulation of dendritic spine development IMP
IMP: 通过突变表型推断
12052877 RGD
involved in positive regulation of long-term synaptic depression IMP
IMP: 通过突变表型推断
16899074 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
9362513 RGD
involved in positive regulation of protein kinase activity IMP
IMP: 通过突变表型推断
9653190 RGD
involved in postsynaptic actin cytoskeleton organization IDA
IDA: 通过直接分析推断
15473970 RGD
involved in postsynaptic actin cytoskeleton organization IMP
IMP: 通过突变表型推断
15473970 RGD
involved in regulation of actin filament polymerization IMP
IMP: 通过突变表型推断
15473970 RGD
involved in regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
15473970 RGD
involved in regulation of filopodium assembly IMP
IMP: 通过突变表型推断
12052877 RGD
involved in regulation of synapse assembly IMP
IMP: 通过突变表型推断
15473970 RGD
involved in regulation of synapse structural plasticity IMP
IMP: 通过突变表型推断
15473970 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
10514494 RGD
located in cytoskeleton IDA
IDA: 通过直接分析推断
16525025 RGD
located in dendrite IDA
IDA: 通过直接分析推断
9362513 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
15473970 RGD
located in dendritic spine neck IDA
IDA: 通过直接分析推断
15473970 RGD
located in filopodium IDA
IDA: 通过直接分析推断
15473970 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15473970 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
15473970 RGD
located in growth cone IDA
IDA: 通过直接分析推断
16525025 RGD
located in growth cone lamellipodium IDA
IDA: 通过直接分析推断
9362513 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
9362513 RGD
located in neuromuscular junction IDA
IDA: 通过直接分析推断
9362513 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
9362513 RGD
is active in postsynaptic actin cytoskeleton IDA
IDA: 通过直接分析推断
15473970 RGD
is active in postsynaptic actin cytoskeleton IMP
IMP: 通过突变表型推断
15473970 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neurabin-1

actin-binding protein neurabin

neurabin-I

neural tissue-specific F-actin-binding protein I

protein phosphatase 1, regulatory (inhibitor) subunit 9A

Ppp1r9a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ppp1r9a O35867 Rps6kb1 Rattus norvegicus P67999
Y2H
9653190
种属内
Ppp1r9a O35867 Ppp1cb Rattus norvegicus P62142
Pull Down
18216290
种属内
Ppp1r9a O35867 Ppp1cc Rattus norvegicus P63088
Pull Down
18216290
种属内
Ppp1r9a O35867 Ppp1cc Rattus norvegicus P63088
Anti Tag CoIP
18216290
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11005 PPP1R9A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp1r9a NCBI NCBI:55607
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z