PPP1R9A - protein phosphatase 1 regulatory subunit 9A Gene

中文名称：蛋白磷酸酶 1 调节亚基 9A

种属: Homo sapiens

同用名: NRB1; NRBI; Neurabin-I

关于 PPP1R9A

功能概要

该基因是印迹基因，位于染色体 7q12 上的一簇印迹基因中。该基因在神经元和多个胚胎组织中均有转录，主要在胚胎骨骼肌组织中以母源方式表达，在其他胚胎组织中以双等位基因表达。该基因编码的蛋白质包括一个 PDZ 结构域和一个不育的 alpha 基序 (SAM) 。它是蛋白磷酸酶 I 的调节亚基，控制肌动蛋白细胞骨架重组。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2009 年 10 月]

This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein Phosphatase I, and controls actin Cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]