Rps6kb1 - ribosomal protein S6 kinase B1 Gene

中文名称：核糖体蛋白 S6 激酶 B1

种属: Rattus norvegicus

同用名: p70 S6K-alpha

关于 Rps6kb1

功能概要

该基因编码的蛋白可启动多项功能，包括 ATP 绑定活动； PDZ 域绑定活动；和蛋白磷酸酶 2A 结合活性。涉及多个过程，包括长期记忆；骨骼肌组织生长的正调节；和对肽激素的反应。位于多个细胞成分中，包括细胞表面；胞质溶胶；和细胞质的核周区。在突触中活跃。多种疾病的生物标志物，包括常染色体显性多囊肾病；高胰岛素血症;肌肉萎缩;肥胖;和原发性胆汁性胆管炎。与人 RPS6KB1（核糖体蛋白 S6 激酶 B1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including ATP binding activity; PDZ domain binding activity; and protein Phosphatase 2A binding activity. Involved in several processes, including long-term memory; positive regulation of skeletal muscle tissue growth; and response to peptide hormone. Located in several cellular components, including cell surface; cytosol; and perinuclear region of cytoplasm. Is active in synapse. Biomarker of several diseases, including autosomal dominant polycystic kidney disease; hyperinsulinism; muscular atrophy; obesity; and primary biliary cholangitis. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, Apr 2022]