Mtor - mechanistic target of rapamycin kinase Gene

中文名称：雷帕霉素激酶的机制靶点

种属: Mus musculus

同用名: FRAP; flat; FRAP2; Frap1; RAFT1; RAPT1; 2610315D21Rik

基因 ID: 56717 | 基因类型: protein coding

关于 Mtor

Chromosome 4: 148,533,068-148,642,140 forward strand.GRCm39:CM000997.3

This gene has 4 transcripts (splice variants), 217 orthologues, 5 paralogues and is associated with 64 phenotypes. Ubiquitous expression in testis adult (RPKM 23.), kidney adult (RPKM 12.8) and 28 other tissues.

功能概要

该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性和核糖体结合活性。参与多个过程，包括“从头”嘧啶核碱基生物合成过程； T-helper 1 细胞谱系承诺；和神经元动作电位。作用于多个过程的上游或内部，包括心脏发育；细胞成分生物合成的正向调节；和蛋白质磷酸化的调节。位于胞质溶胶中；树突;和核。 TORC1 复合体的一部分。与 PML 体共定位。在中枢神经系统中表达；早孕;卵母细胞;呼吸系统;和视网膜。该基因的人类直系同源物与常染色体显性多囊肾病有关；肾血管平滑肌脂肪瘤;肺部疾病（多发）；前列腺癌;和 2 型糖尿病。与人 mTOR 同源（雷帕霉素激酶的机制靶标）。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein serine/threonine kinase activity and ribosome binding activity. Involved in several processes, including 'de novo' pyrimidine nucleobase biosynthetic process; T-helper 1 cell lineage commitment; and neuronal action potential. Acts upstream of or within several processes, including heart development; positive regulation of cellular component biogenesis; and regulation of protein phosphorylation. Located in cytosol; dendrite; and nucleus. Part of TORC1 complex. Colocalizes with PML body. Is expressed in central nervous system; early conceptus; oocyte; respiratory system; and retina. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; kidney angiomyolipoma; lung disease (multiple); prostate cancer; and type 2 diabetes mellitus. Orthologous to human mTOR (mechanistic target of rapamycin kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mtor 基因产物(1)

mRNA	Protein	Name
NM_020009.2	NP_064393.2	serine/threonine-protein kinase mTOR

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	12150926	MGI
enables protein serine/threonine kinase activity	IDA IDA: 通过直接分析推断	11707573	MGI
enables ribosome binding	IDA IDA: 通过直接分析推断	21045808	MGI

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in 'de novo' pyrimidine nucleobase biosynthetic process	IDA IDA: 通过直接分析推断	23429704	MGI
involved in T-helper 1 cell lineage commitment	IMP IMP: 通过突变表型推断	26410627	MGI
involved in TOR signaling	IGI IGI: 通过遗传相互作用推断	26160071	MGI
involved in TOR signaling	IMP IMP: 通过突变表型推断	15485918	MGI
involved in behavioral response to pain	IGI IGI: 通过遗传相互作用推断	31874168	MGI
acts upstream of calcineurin-NFAT signaling cascade	IMP IMP: 通过突变表型推断	18347059	MGI
involved in cardiac cell development	IMP IMP: 通过突变表型推断	23342106	MGI
acts upstream of or within cardiac muscle cell development	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within cardiac muscle contraction	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within cardiac muscle tissue development	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within cell projection organization	IMP IMP: 通过突变表型推断	16286931	MGI
involved in cellular response to hypoxia	IDA IDA: 通过直接分析推断	16915281	MGI
involved in cellular response to nutrient levels	IDA IDA: 通过直接分析推断	21258367	MGI
acts upstream of or within energy reserve metabolic process	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within germ cell development	IDA IDA: 通过直接分析推断	12140361	MGI
acts upstream of or within heart morphogenesis	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within heart valve morphogenesis	IMP IMP: 通过突变表型推断	25139234	MGI
involved in inflammatory response	IGI IGI: 通过遗传相互作用推断	31874168	MGI
acts upstream of macroautophagy	IMP IMP: 通过突变表型推断	16714284	MGI
acts upstream of or within multicellular organism growth	IMP IMP: 通过突变表型推断	25139234	MGI
involved in negative regulation of autophagy	IMP IMP: 通过突变表型推断	21258367	MGI
acts upstream of or within negative regulation of calcineurin-NFAT signaling cascade	IMP IMP: 通过突变表型推断	18347059	MGI
acts upstream of or within negative regulation of cell size	IGI IGI: 通过遗传相互作用推断	15185396	MGI
acts upstream of or within negative regulation of macroautophagy	IMP IMP: 通过突变表型推断	16714284	MGI
involved in neuronal action potential	IGI IGI: 通过遗传相互作用推断	31874168	MGI
acts upstream of oligodendrocyte differentiation	IMP IMP: 通过突变表型推断	25411504	MGI
involved in peptidyl-serine phosphorylation	IDA IDA: 通过直接分析推断	24011591	MGI
acts upstream of or within peptidyl-serine phosphorylation	IMP IMP: 通过突变表型推断	18347059	MGI
acts upstream of or within peptidyl-threonine phosphorylation	IDA IDA: 通过直接分析推断	11707573	MGI
acts upstream of or within positive regulation of actin filament polymerization	IDA IDA: 通过直接分析推断	15467718	MGI
acts upstream of or within positive regulation of actin filament polymerization	IMP IMP: 通过突变表型推断	15467718	MGI
acts upstream of or within positive regulation of lamellipodium assembly	IDA IDA: 通过直接分析推断	15467718	MGI
acts upstream of or within positive regulation of myotube differentiation	IGI IGI: 通过遗传相互作用推断	19704009	MGI
acts upstream of or within positive regulation of oligodendrocyte differentiation	IMP IMP: 通过突变表型推断	25411504	MGI
acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation	IMP IMP: 通过突变表型推断	15467718	MGI
acts upstream of or within positive regulation of protein phosphorylation	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within positive regulation of stress fiber assembly	IDA IDA: 通过直接分析推断	15467718	MGI
acts upstream of or within post-embryonic development	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within regulation of GTPase activity	IMP IMP: 通过突变表型推断	15467718	MGI
involved in regulation of autophagy	IDA IDA: 通过直接分析推断	24011591	MGI
involved in regulation of circadian rhythm	IMP IMP: 通过突变表型推断	29750810	MGI
involved in regulation of locomotor rhythm	IMP IMP: 通过突变表型推断	29750810	MGI
acts upstream of or within regulation of membrane permeability	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within regulation of myelination	IMP IMP: 通过突变表型推断	24101522	MGI
involved in regulation of osteoclast differentiation	IDA IDA: 通过直接分析推断	19440205	MGI
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP IMP: 通过突变表型推断	25139234	MGI
acts upstream of or within regulation of protein kinase activity	IGI IGI: 通过遗传相互作用推断	15185396	MGI
acts upstream of or within regulation of protein phosphorylation	IDA IDA: 通过直接分析推断	17556672	MGI
acts upstream of or within response to amino acid	IDA IDA: 通过直接分析推断	15467718	MGI
involved in response to heat	IGI IGI: 通过遗传相互作用推断	31874168	MGI
acts upstream of or within response to insulin	IDA IDA: 通过直接分析推断	15467718	MGI
acts upstream of or within ruffle organization	IDA IDA: 通过直接分析推断	15467718	MGI
acts upstream of or within voluntary musculoskeletal movement	IMP IMP: 通过突变表型推断	25139234	MGI

细胞组分 GO 注释	逻辑证据	参考文献	来源
colocalizes with PML body	IDA IDA: 通过直接分析推断	16915281	MGI
part of TORC1 complex	IDA IDA: 通过直接分析推断	12718876	MGI
located in cytosol	IDA IDA: 通过直接分析推断	16915281	MGI
located in dendrite	IDA IDA: 通过直接分析推断	23836929	MGI
located in nucleus	IDA IDA: 通过直接分析推断	18347059	MGI

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Mtor 蛋白结构

TEL1

HEAT

0
400
800
1200
1600
2000
2400
2549 a.a.

蛋白主名

其他名称

serine/threonine-protein kinase mTOR

FK506 binding protein 12-rapamycin associated protein 1	FK506-binding protein 12-rapamycin complex-associated protein 1
FKBP-rapamycin associated protein (FRAP)	FKBP12-rapamycin complex-associated protein
angiopoietin-like factor CDT6	mammalian target of rapamycin
mechanistic target of rapamycin (serine/threonine kinase)	rapamycin target protein 1

Mtor 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属间	Mtor	Q9JLN9	RPTOR	Homo sapiens	Q8N122	Anti Tag CoIP	24036451
种属内	Mtor	Q9JLN9	Eif3f	Mus musculus	Q9DCH4	Pull Down	16541103
种属内	Mtor	Q9JLN9	Rictor	Mus musculus	Q6QI06	Anti Bait CoIP	20801936
种属内	Mtor	Q9JLN9	Rictor	Mus musculus	Q6QI06	Anti Tag CoIP	18566586
种属内	Mtor	Q9JLN9	Rictor	Mus musculus	Q6QI06	Anti Bait CoIP	21045808
种属内	Mtor	Q9JLN9	Rictor	Mus musculus	Q6QI06	Density Sedimentation	21045808
种属内	Mtor	Q9JLN9	Rictor	Mus musculus	Q6QI06	Anti Bait CoIP	18664580
种属内	Mtor	Q9JLN9	Rptor	Mus musculus	Q8K4Q0	Anti Bait CoIP	21045808
种属内	Mtor	Q9JLN9	Rptor	Mus musculus	Q8K4Q0	Anti Tag CoIP	20801936
种属内	Mtor	Q9JLN9	Rptor	Mus musculus	Q8K4Q0	Anti Bait CoIP	23966835
种属内	Mtor	Q9JLN9	Rptor	Mus musculus	Q8K4Q0	Density Sedimentation	21045808
种属内	Mtor	Q9JLN9	Rptor	Mus musculus	Q8K4Q0	Anti Bait CoIP	18664580
种属内	Mtor	Q9JLN9	Rptor	Mus musculus	Q8K4Q0	Anti Bait CoIP	20801936

种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Approval

生物活性分子 (9)

目录号	产品名	作用方式	纯度	是否罕见病
HY-10219	Rapamycin	Inhibitor	99.94%	是
HY-10218	Everolimus	Inhibitor	99.85%	是
HY-50910	Temsirolimus	Inhibitor	99.56%	是
HY-N0486	L-Leucine	Activator	99.79%	否
HY-N0281	Daphnetin	Inhibitor	99.86%	否
HY-B0766	Bicyclol		99.91%	否
HY-B1232A	Metyrapone Tartrate	Modulator	/	否
HY-B0725A	Doxepin		/	否
HY-10218R	Everolimus (Standard)	Inhibitor	/	否

Clinical Phase

生物活性分子 (33)

目录号	产品名	作用方式	纯度	Phase
HY-10219G	Rapamycin (GMP)	Inhibitor	/	Phase 4
HY-50673	Dactolisib	Inhibitor	99.94%	Phase 3
HY-10681	Gedatolisib	Inhibitor	99.68%	Phase 3
HY-15174	Dactolisib Tosylate	Inhibitor	99.87%	Phase 3
HY-50908	Ridaforolimus	Inhibitor	99.75%	Phase 3
HY-13328	Sapanisertib	Inhibitor	99.66%	Phase 2
HY-139609	Camonsertib	Inhibitor	99.75%	Phase 2
HY-N0112	Dihydromyricetin	Inhibitor	98.10%	Phase 2
HY-114384	NV-5138	Activator	≥98.0%	Phase 2
HY-15247	Vistusertib	Inhibitor	99.32%	Phase 2
HY-15177	PF-04691502	Inhibitor	99.91%	Phase 2
HY-12513	Samotolisib	Inhibitor	99.27%	Phase 2
HY-114384B	NV-5138 hydrochloride	Activator	≥98.0%	Phase 2
HY-13246	Apitolisib	Inhibitor	99.29%	Phase 2
HY-15900	Voxtalisib	Inhibitor	98.81%	Phase 2
HY-12868	Bimiralisib	Inhibitor	99.80%	Phase 2
HY-16956	Onatasertib	Inhibitor	99.13%	Phase 2
HY-13334A	BGT226	Inhibitor	99.51%	Phase 2
HY-10423	OSI-027	Inhibitor	99.40%	Phase 2
HY-N9481	Lipoteichoic acid	Inhibitor	/	Phase 2
HY-13334	BGT226 maleate	Inhibitor	99.87%	Phase 2
HY-13691	MKC-1	Inhibitor	99.23%	Phase 2
HY-10422	AZD-8055	Inhibitor	99.60%	Phase 1
HY-132168	RMC-5552	Inhibitor	98.10%	Phase 1
HY-10297	Omipalisib	Inhibitor	99.93%	Phase 1
HY-16962	CC-115	Inhibitor	99.82%	Phase 1
HY-12036	GSK1059615	Inhibitor	≥99.0%	Phase 1
HY-16585	VS-5584	Inhibitor	99.14%	Phase 1
HY-16962A	CC-115 hydrochloride	Inhibitor	98.03%	Phase 1
HY-14581	Palomid 529	Inhibitor	99.37%	Phase 1
HY-15248	GDC-0349	Inhibitor	98.02%	Phase 1
HY-126077	MTI-31	Inhibitor	99.98%	Phase 1
HY-124036	DS-7423	Inhibitor	99.75%	Phase 1

Pre-clinical Phase

生物活性分子 (212)

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-B0795	MHY1485	Activator	99.86%	否
HY-13003	Torin 1	Inhibitor	99.08%	否
HY-N0109	Salidroside	Activator	99.90%	否
HY-13002	Torin 2	Inhibitor	99.65%	否
HY-10115	PI-103	Inhibitor	98.93%	否
HY-111373	RapaLink-1	Inhibitor	99.27%	否
HY-122022	JR-AB2-011	Inhibitor	99.16%	否
HY-U00434	3BDO	Activator	99.93%	否
HY-10474	Torkinib	Inhibitor	98.29%	否
HY-100542	D-α-Hydroxyglutaric acid disodium	Inhibitor	≥98.0%	否
HY-124719	hSMG-1 inhibitor 11j	Inhibitor	99.82%	否
HY-N0189	Aloe emodin	Inhibitor	98.32%	否
HY-124798	Rheb inhibitor NR1	Inhibitor	99.03%	否
HY-N0047	Polyphyllin I	Inhibitor	99.89%	否
HY-N0787	Cryptochlorogenic acid	Inhibitor	99.87%	否
HY-50710	KU-0063794	Inhibitor	99.55%	否
HY-W012722	4-Methyl-2-oxopentanoic acid	Inhibitor	99.51%	否
HY-116522	AR420626		98.29%	否
HY-19962	Paxalisib	Inhibitor	99.63%	是
HY-124760	hSMG-1 inhibitor 11e	Inhibitor	99.81%	否
HY-155747	FDW028	Inhibitor	99.51%	否
HY-134904	RMC-6272	Inhibitor	95.54%	否
HY-10044	WYE-132	Inhibitor	99.90%	否
HY-N0486S1	L-Leucine-13C	Activator	99.4%	否
HY-13431	KU-0060648	Inhibitor	99.62%	否
HY-115449	Chromeceptin	p53 Inhibitor	99.80%	否
HY-N0486S9	L-Leucine-d3	Activator	99.93%	否
HY-10372	PP121	Inhibitor	98.67%	否
HY-N6626	Pyraclostrobin		99.91%	否
HY-10683	PKI-402	Inhibitor	98.43%	否
HY-18353	mTOR inhibitor-3	Inhibitor	99.09%	否
HY-146751	PI3K/Akt/mTOR-IN-2	Inhibitor	99.86%	否
HY-100222	CZ415	Inhibitor	98.39%	否
HY-N6996	Methyl Eugenol	Inhibitor	99.79%	否
HY-W592871	10-Hydroxy-2-decenoic acid		99.99%	否
HY-12763	GNE-317	Inhibitor	99.14%	否
HY-107365	PQR530	Inhibitor	99.98%	否
HY-N0107	Cyclovirobuxine D	Inhibitor	≥98.0%	否
HY-15521	ETP-46464	Inhibitor	99.55%	否
HY-W016412	Coenzyme Q0	Inhibitor	99.88%	否
HY-10115A	PI-103 Hydrochloride	Inhibitor	98.55%	否
HY-15272	WAY-600	Inhibitor	99.75%	否
HY-156671	RMC-4998	Inhibitor	96.33%	否
HY-N0486S8	L-Leucine-13C6,15N	Activator	99.90%	否
HY-N0656A	(+)-Usnic acid	Inhibitor	99.63%	否
HY-N0486S	L-Leucine-d10	Activator	≥98.0%	否
HY-N0486S3	L-Leucine-15N	Activator	≥98.0%	否
HY-10219S	Rapamycin-d3	Inhibitor	95.48%	否
HY-100026	PQR620	Inhibitor	98.01%	否
HY-12034	WYE-354	Inhibitor	98.04%	否
HY-N6843	Arnicolide D	Inhibitor	99.20%	否
HY-10811	GNE-493	Inhibitor	99.81%	否
HY-100470	NSC781406	Inhibitor	99.97%	否
HY-114414	HDACs/mTOR Inhibitor 1	Inhibitor	99.01%	否
HY-100398	PF-04979064	Inhibitor	99.54%	否
HY-W058849	MT 63-78	Inhibitor	98.50%	否
HY-112914	mTOR inhibitor-1	Inhibitor	98.82%	否
HY-111508	PI3K/mTOR Inhibitor-2	Inhibitor	99.10%	否
HY-131344	mTOR inhibitor-8	Inhibitor	98.14%	否
HY-11080	PKI-179	Inhibitor	≥98.0%	否
HY-110109	ETP-45658	Inhibitor	98.97%	否
HY-N2217	Rotundic acid	Inhibitor	99.41%	否
HY-N6950	Hederacolchiside A1	Modulator	99.69%	否
HY-11042	GNE-477	Inhibitor	98.75%	否
HY-118717	mTOR inhibitor WYE-28	Inhibitor	99.75%	否
HY-137175	TMBIM6 antagonist-1	Antagonist	99.60%	否
HY-109046	Tulrampator		98.92%	否
HY-159480	AD1058	Inhibitor	98.11%	否
HY-128333	PI3K/mTOR Inhibitor-4	Inhibitor	97.00%	否
HY-N1050	Zederone	Inhibitor	99.61%	否
HY-N9942	Physalin A	Inhibitor	99.22%	否
HY-15271	WYE-687	Inhibitor	98.05%	否
HY-13806	XL388	Inhibitor	99.74%	否
HY-136660	PQR626	Inhibitor	98.05%	否
HY-163198	ASCT2-IN-1	Inhibitor	98.21%	否
HY-12652	AZD3147	Inhibitor	99.93%	否
HY-124582	NEO214	Activator	≥98.0%	否
HY-122665	HTH-01-091	Inhibitor	98.64%	否
HY-163199	ASCT2-IN-2	Inhibitor	99.10%	否
HY-137315	TML-6	Inhibitor	99.01%	否
HY-145931	CC214-2	Inhibitor	98.41%	否
HY-W348485	WRX606	Inhibitor	95.65%	否
HY-N0486S2	L-Leucine-13C6	Activator	≥98.0%	否
HY-11080A	PKI-179 hydrochloride	Inhibitor	99.66%	否
HY-125927	8-Aminoadenosine	Inhibitor	99.94%	否
HY-134903	(32-Carbonyl)-RMC-5552	Inhibitor	95.41%	否
HY-151622	PI3K/mTOR Inhibitor-11	Inhibitor	98.74%	否
HY-107363	FT-1518	Inhibitor	98.14%	否
HY-114267	Cbz-B3A	Inhibitor	≥98.0%	否
HY-153120A	PI3K/mTOR Inhibitor-13 sodium	Inhibitor	98.13%	否
HY-B1787	Sulindac sulfone	Inhibitor	98.08%	否
HY-162382	KTC1101	Inhibitor	98.09%	否
HY-N2590	Lupenone		99.74%	否
HY-141805	MHY-1685	Inhibitor	99.97%	否
HY-111065	OXA-01	Inhibitor	/	否
HY-101776A	Desmethyl-VS-5584 hydrochloride	Inhibitor	98.63%	否
HY-10219GL	Rapamycin (GMP Like)	Inhibitor	98.8%	否
HY-N3628	Coronarin A	Inhibitor	≥98.0%	否
HY-155066	FD274	Inhibitor	99.45%	否
HY-109633	PI3K-IN-18	Inhibitor	≥99.0%	否
HY-122665A	HTH-01-091 TFA	Inhibitor	99.48%	否
HY-N4315	Pomiferin	Inhibitor	98.98%	否
HY-157169	IBL-302	Inhibitor	98.21%	否
HY-15271A	WYE-687 dihydrochloride	Inhibitor	≥98.0%	否
HY-N0486S12	L-Leucine-d2	Activator	≥99.0%	否
HY-143510	RMC-4627		99.20%	否
HY-156027	SIRT6-IN-3	Inhibitor	98.19%	否
HY-N5136	25(R,S)-Ruscogenin	Inhibitor	99.83%	否
HY-147284	PI3K-IN-37	Inhibitor	≥99.0%	否
HY-10620	PI3K-IN-22	Inhibitor	99.50%	否
HY-U00326	PI3Kα/mTOR-IN-1	Inhibitor	99.30%	否
HY-10812	GNE-490	Inhibitor	96.29%	否
HY-151137	HSP90/mTOR-IN-1	Inhibitor	/	否
HY-10218S	Everolimus-d4	Inhibitor	97.88%	否
HY-139832	MCX 28	Inhibitor	/	否
HY-161509	PT-88	Inhibitor	/	否
HY-128027	eCF309	Inhibitor	98.2%	否
HY-147913	PI3K/Akt/mTOR-IN-3	Inhibitor	/	否
HY-144687	ATM Inhibitor-4	Inhibitor	/	否
HY-146016	PI3K/mTOR Inhibitor-5	Inhibitor	/	否
HY-N0486S10	L-Leucine-18O2	Activator	/	否
HY-154910	CC214-1	Inhibitor	/	否
HY-N0486S6	L-Leucine-2-13C,15N	Activator	/	否
HY-163511	PI3K/Akt/mTOR-IN-4	Inhibitor	/	否
HY-161856	Antifungal agent 106	Inhibitor	/	否
HY-150061	NVP-BBD130	Inhibitor	/	否
HY-169100	Antiproliferative agent-57		/	否
HY-155376	mTOR inhibitor-14	Inhibitor	/	否
HY-RS08811	Mtor Mouse Pre-designed siRNA Set A	Inhibitor	/	否
HY-N10754	Aschantin	Inhibitor	/	否
HY-160548	mTOR inhibitor-18	Inhibitor	/	否
HY-N2517	Dihydroevocarpine	Inhibitor	99.62%	否
HY-15281	QL-IX-55	Inhibitor	/	否
HY-RS08812	Mtor Rat Pre-designed siRNA Set A	Inhibitor	/	否
HY-15901	LGB321	Inhibitor	/	否
HY-141476	PI3K/mTOR Inhibitor-3	Inhibitor	/	否
HY-162147	Nur77 modulator 3	Inhibitor	99.01%	否
HY-N0486S13	L-Leucine-15N,d10		/	否
HY-13847	GNE-555	Inhibitor	/	否
HY-162143	SKI-349	Inhibitor	99.58%	否
HY-101776	Desmethyl-VS-5584	Inhibitor	/	否
HY-168609	CRI9	Inhibitor	/	否
HY-162993	HN2210	Inhibitor	/	否
HY-169022	4-FPBUA	Inhibitor	/	否
HY-141701	mTOR/HDAC-IN-1	Inhibitor	/	否
HY-118712	mTOR inhibitor WYE-23	Inhibitor	/	否
HY-113038	D-α-Hydroxyglutaric acid	Inhibitor	/	否
HY-137315S	TML-6-d3		/	否
HY-N0486S4	L-Leucine-d7	Activator	/	否
HY-154958	mTOR inhibitor-12	Inhibitor	/	否
HY-18953	mTOR inhibitor-23	Inhibitor	/	否
HY-P5984	Thioether-cyclized helix B peptide, CHBP	Inhibitor	/	否
HY-147285	PI3K/mTOR Inhibitor-9	Inhibitor	/	否
HY-168333	5-HT6 inverse agonist 1	Inhibitor	/	否
HY-15269	PP30	Inhibitor	/	否
HY-118704	P-2281	Inhibitor	99.81%	否
HY-147614	PI3K/mTOR Inhibitor-7	Inhibitor	/	否
HY-154957	mTOR inhibitor-11	Inhibitor	/	否
HY-N0486S7	L-Leucine-1-13C,15N	Activator	≥98.0%	否
HY-P1823	C-Reactive Protein (CRP) (174-185)	Modulator	99.83%	否
HY-N0486S11	L-Leucine-d1	Activator	/	否
HY-137996	Dehydrovomifoliol	Inhibitor	/	否
HY-115869	RMC-4529	Inhibitor	/	否
HY-127067	Yuanhuadin	Inhibitor	/	否
HY-125535	OSU-53	Inhibitor	/	否
HY-146200	PI3K/mTOR Inhibitor-8	Inhibitor	/	否
HY-151915	ATR-IN-20	Inhibitor	/	否
HY-159517	PI3K/Akt/mTOR-IN-5	Inhibitor	/	否
HY-P10323	T7 Peptide	Inhibitor	/	否
HY-N1244	Sarmentosin	Inhibitor	/	否
HY-159577	Nic-15	Modulator	/	否
HY-147613	PI3K/mTOR Inhibitor-6	Inhibitor	/	否
HY-156432	ALK-IN-26	Inhibitor	99.87%	否
HY-N6626R	Pyraclostrobin (Standard)		/	否
HY-156445	PI3K/mTOR Inhibitor-14	Inhibitor	/	否
HY-147966	HDAC-IN-43	Inhibitor	/	否
HY-144295	PI3Kα-IN-5	Inhibitor	/	否
HY-144449	mTOR/HDAC6-IN-1	Inhibitor	/	否
HY-121726	3HOI-BA-01	Inhibitor	/	否
HY-144686	ATM Inhibitor-3	Inhibitor	/	否
HY-152238	PI3K/mTOR Inhibitor-12	Inhibitor	/	否
HY-P5984A	Thioether-cyclized helix B peptide, CHBP TFA	Inhibitor	/	否
HY-155721	22-(4′-py)-JA	Inhibitor	/	否
HY-N1338	Royleanone	Inhibitor	/	否
HY-N0486S5	L-Leucine-2-13C	Activator	/	否
HY-10116	PI-540	Inhibitor	/	否
HY-15268	PP487	Inhibitor	/	否
HY-161857	Akt/mTOR-IN-1	Inhibitor	/	否
HY-RS08810	MTOR Human Pre-designed siRNA Set A	Inhibitor	/	否
HY-15901A	LGB321 monohydrochloride	Inhibitor	/	否
HY-123849	SN32976	Inhibitor	/	否
HY-N12124	Monascuspiloin	Inhibitor	/	否
HY-153120	PI3K/mTOR Inhibitor-13	Inhibitor	/	否
HY-169121	DA-143	Inhibitor	/	否
HY-N0109R	Salidroside (Standard)	Activator	/	否
HY-162023	mTOR inhibitor-10	Inhibitor	/	否
HY-N13176	Stellettin B	Inhibitor	/	否
HY-164385	NSC126405	Inhibitor	/	否
HY-155211	mTOR inhibitor-13	Inhibitor	/	否
HY-164384	DFX117	Inhibitor	/	否
HY-162024	mTOR inhibitor-16	Inhibitor	/	否
HY-116191	WJD008	Inhibitor	/	否
HY-164662	mTOR inhibitor-24	Inhibitor	/	否
HY-155475	mTORC1-IN-2	Inhibitor	/	否
HY-117923	PF-06465603	Inhibitor	/	否
HY-50673A	Dactolisib hydrochloride	Inhibitor	/	否
HY-W779800	D-α-Hydroxyglutaric acid-13C5 disodium	Inhibitor	/	否
HY-162025	mTOR inhibitor-17	Inhibitor	/	否
HY-W654330	Pyraclostrobin-d6		/	否
HY-112602	PI3K/mTOR Inhibitor-1	Inhibitor	/	否
HY-111370	mTOR inhibitor-2	Inhibitor	/	否
HY-101955	(2S,6S)-Hydroxynorketamine hydrochloride	Activator	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Mtor	NCBI	NCBI:2475

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