2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. VGB3

VGB3 是血管内皮生长因子受体 1 (VEGFR1)/VEGFR2 的拮抗剂肽，具有抗血管生成和抗肿瘤作用。VGB3 结合 VEGFR1 和 VEGFR2，从而抑制 VEGF 驱动的内皮细胞增殖、迁移和管状形成，以及在小鼠 4T1 乳腺癌肿瘤模型中抑制肿瘤的生长和转移。

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VGB3 Chemical Structure

VGB3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

VGB3 相关抗体

Top Publications Citing Use of Products

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VGB3 is an antagonist peptide of vascular endothelial growth factor receptor 1 (VEGFR1)/VEGFR2 with antiangiogenic and antitumor effects. VGB3 binds to both VEGFR1 and VEGFR2, thereby inhibits VEGF-driven proliferation, migration and tube formation of endothelial cells, and tumor growth and metastasis in murine 4T1 mammary carcinoma tumor model[1].

IC50 & Target

VEGFR1

 

VEGFR2

 

分子量

1572.76

Formula

C67H101N19O21S2
Sequence

Lys-Ala-Trp-Ala-Glu-Cys-Arg-Pro-Pro-Asp-Glu-Gly-Leu-Cys (Disulfide bridge: Cys6-Cys14)
Sequence Shortening

KAWAECRPPDEGLC (Disulfide bridge: Cys6-Cys14)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VGB3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VGB3VGB 3VGB-3VEGFRVascular endothelial growth factor receptorVEGFR1VEGFR2antiangiogenicendothelial cellscarcinoma tumor modelInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P10833
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