2. Gene
  3. SYNGR3 - synaptogyrin 3 Gene

SYNGR3 - synaptogyrin 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：突触蛋白 3

种属: Homo sapiens

基因 ID: 9143 | 基因类型: protein coding

关于 SYNGR3

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:1,989,970-1,994,275 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 3 paralogues. Biased expression in brain (RPKM 26.0), adrenal (RPKM 4.5) and 2 other tissues.

功能概要

该基因编码一种完整的膜蛋白。这种蛋白质的确切功能尚不清楚，但对类似鼠类蛋白质的研究表明，它是一种突触小泡蛋白，也与多巴胺转运蛋白相互作用。该基因产物属于突触蛋白基因家族。[RefSeq 提供，2010 年 12 月]

This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the Dopamine Transporter. The gene product belongs to the synaptogyrin gene family. [provided by RefSeq, Dec 2010]

SYNGR3 基因产物(1)

mRNA Protein Name
NM_004209.6 NP_004200.2 synaptogyrin-3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SYNGR3 蛋白结构

MARVEL

MARVEL: Membrane-associating domain (21 - 165)

  • 0
  • 100
  • 200
  • 229 a.a.
蛋白主名 其他名称

synaptogyrin-3

SYNGR3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SYNGR3 O43761 TTPA Homo sapiens P49638
Validated Y2H
32296183
Intra SYNGR3 O43761 PNKP Homo sapiens Q96T60
Validated Y2H
32296183
Intra SYNGR3 O43761 NDRG4 Homo sapiens Q9ULP0-2
Validated Y2H
32296183
Intra SYNGR3 O43761 EHHADH Homo sapiens Q08426
Validated Y2H
32296183
Intra SYNGR3 O43761 SH3GLB1 Homo sapiens Q9Y371
Validated Y2H
32296183
Intra SYNGR3 O43761 ARFIP1 Homo sapiens P53367
Validated Y2H
32296183
Intra SYNGR3 O43761 ACSF2 Homo sapiens Q96CM8
Validated Y2H
32296183
Intra SYNGR3 O43761 YWHAG Homo sapiens P61981
Y2H Array
32814053
Intra SYNGR3 O43761 YWHAG Homo sapiens P61981
Y2H Pooling
32814053
Intra SYNGR3 O43761 YWHAG Homo sapiens P61981
Validated Y2H
32814053
Intra SYNGR3 O43761 MPP1 Homo sapiens Q00013
Validated Y2H
32296183
Intra SYNGR3 O43761 MIDN Homo sapiens Q504T8
Validated Y2H
32296183
Intra SYNGR3 O43761 PLIN3 Homo sapiens O60664
Validated Y2H
32296183
Intra SYNGR3 O43761 SPG21 Homo sapiens Q9NZD8
Validated Y2H
32296183
Intra SYNGR3 O43761 SETDB1 Homo sapiens Q15047-2
Y2H Array
32814053
Intra SYNGR3 O43761 SETDB1 Homo sapiens Q15047-2
Y2H Pooling
32814053
Intra SYNGR3 O43761 SETDB1 Homo sapiens Q15047-2
Validated Y2H
32814053
Intra SYNGR3 O43761 GAD2 Homo sapiens Q05329
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Deafness, Autosomal Recessive 86

DFNB86

Autosomal Recessive Nonsyndromic Deafness 86

Autosomal Recessive Deafness 86

Deafness, Autosomal Recessive, 86

Deafness, Nonsyndromic, Autosomal Recessive, Type 86
Generalized Atherosclerosis

Generalised Atherosclerosis
Pick Disease Of Brain

Pick Disease

Pick'S Disease

Pick Disease Of The Brain

Lobar Atrophy Of Brain

Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions

Behavioral Variant Of Frontotemporal Dementia

Dementia In Pick'S Disease

Lobar Atrophy Of The Brain

Bvftd

Bv-Ftd

PIDB

Picks Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14092 SYNGR3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SYNGR3 VGNC VGNC:80687
Macaca mulatta SYNGR3 VGNC VGNC:78069
Rattus norvegicus SYNGR3 RGD RGD:1311801
Mus musculus SYNGR3 MGD MGI:1341881
Bos taurus SYNGR3 VGNC VGNC:35525
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