ACY3 - aminoacylase 3 Gene

中文名称：氨基酰化酶 3

种属: Homo sapiens

同用名: ACY-3; HCBP1

基因 ID: 91703 | 基因类型: protein coding

关于 ACY3

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:67,642,555-67,650,730 (from NCBI)

This gene has 2 transcripts (splice variants), 232 orthologues and 1 paralogue. Biased expression in kidney (RPKM 28.0), duodenum (RPKM 26.6) and 8 other tissues.

功能概要

预测可启用氨酰化酶活性。位于细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable aminoacylase activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

ACY3 基因产物(1)

mRNA	Protein	Name
NM_080658.2	NP_542389.1	N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	21516116	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACY3 蛋白结构

AstE_AspA

0
100
200
300
319 a.a.

蛋白主名

其他名称

N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)

HCV core-binding protein 1

ACY3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	ACY3	Q96HD9	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	25416956
种属内	ACY3	Q96HD9	KRTAP10-8	Homo sapiens	P60410	Y2H Array	25416956
种属内	ACY3	Q96HD9	PMM2	Homo sapiens	O15305	Validated Y2H	25416956
种属内	ACY3	Q96HD9	AAMDC	Homo sapiens	Q9H7C9	Validated Y2H	25416956
种属内	ACY3	Q96HD9	AAMDC	Homo sapiens	Q9H7C9	Y2H Array	25416956
种属内	ACY3	Q96HD9	KRTAP15-1	Homo sapiens	Q3LI76	Y2H Array	32296183
种属内	ACY3	Q96HD9	KRTAP15-1	Homo sapiens	Q3LI76	Y2H Prey Pooling	32296183
种属内	ACY3	Q96HD9	PIAS2	Homo sapiens	O75928	Y2H Prey Pooling	25416956
种属内	ACY3	Q96HD9	PIAS2	Homo sapiens	O75928	Validated Y2H	25416956
种属内	ACY3	Q96HD9	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
种属内	ACY3	Q96HD9	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
种属内	ACY3	Q96HD9	KRTAP26-1	Homo sapiens	Q6PEX3	Y2H Prey Pooling	32296183
种属内	ACY3	Q96HD9	KRTAP26-1	Homo sapiens	Q6PEX3	Y2H Array	32296183
种属内	ACY3	Q96HD9	ARF5	Homo sapiens	P84085	Y2H Array	32296183
种属内	ACY3	Q96HD9	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
种属内	ACY3	Q96HD9	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	25416956
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	32296183
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	32296183
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	25416956
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	32296183
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	29892012
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Y2H	21516116
种属内	ACY3	Q96HD9	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	31515488
种属内	ACY3	Q96HD9	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	25416956
种属内	ACY3	Q96HD9	LNX1	Homo sapiens	Q8TBB1	Y2H Array	25416956
种属内	ACY3	Q96HD9	LNX1	Homo sapiens	Q8TBB1	Y2H Prey Pooling	25416956
种属内	ACY3	Q96HD9	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
种属内	ACY3	Q96HD9	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
种属内	ACY3	Q96HD9	PLEKHF2	Homo sapiens	Q9H8W4	Validated Y2H	25416956
种属内	ACY3	Q96HD9	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Prey Pooling	25416956
种属内	ACY3	Q96HD9	ASPA	Homo sapiens	P45381	Y2H Array	25416956
种属内	ACY3	Q96HD9	ASPA	Homo sapiens	P45381	Y2H Array	32296183
种属内	ACY3	Q96HD9	NOTCH2NLA	Homo sapiens	Q7Z3S9	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 ACY3 蛋白

目录号	产品名	蛋白编号	纯度
HY-P7457	ACY3 Protein, Human (His)	Q96HD9 (M1-S319)	≥95%

关联疾病

疾病名称

别名

Hepatitis C Virus

Hepatitis C Virus, Susceptibility To	Hepatitis C Virus Infection, Response To Therapy Of
Hcv	Hcv, Susceptibility To
Hepatitis C Virus, Resistance To	Hepatitis C Virus, Response To Therapy Of
Resistance To Hepatitis C Virus

Canavan Disease

Aspartoacylase Deficiency	Aminoacylase 2 Deficiency
Spongy Degeneration Of Central Nervous System	Aspa Deficiency
Acy2 Deficiency	Canavan-Van Bogaert-Bertrand Disease
Mild Canavan Disease	Asp Deficiency
Spongy Degeneration Of The Central Nervous System	Severe Canavan Disease
Von Bogaert-Bertrand Disease	Canavan'S Disease
Spongy Degeneration Of The Brain	Juvenile Canavan Disease
Infantile Canavan Disease	Neonatal Canavan Disease
CAND	Disease, Canavan
Canavan Disease, Juvenile	Canavan Disease, Infantile
Canavan Disease, Neonatal

Leukodystrophy, Hypomyelinating, 2

Pmld1	Hypomyelinating Leukodystrophy 2
HLD2	Pelizaeus-Merzbacher-Like Disease 1
Pelizaeus-Merzbacher-Like Disease Due To Gjc2 Mutation	Pelizaeus-Merzbacher-Like Disease Type 1
Pelizaeus-Merzbacher-Like Disease, 1	Pelizaeus Merzbacher Like Disease
Pelizaeus-Merzbacher-Like Disease	Pmld - Pelizaeus Merzbacher Like Disease
Pelizaeus-Merzbacher-Like Disease Autosomal Recessive Type 1	Pmldar1
Leukodystrophy, Hypomyelinating, Type 2

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-NP042	Protein A-Cy3		/	否
HY-RS00255	ACY3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	ACY3	RGD	RGD:1305394
Macaca mulatta	ACY3	VGNC	VGNC:99538
Mus musculus	ACY3	MGD	MGI:1918920
Others	ACY3	NCBI

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4