NFE2L3 - NFE2 like bZIP transcription factor 3 Gene

中文名称：NFE2 样 bZIP 转录因子 3

种属: Homo sapiens

同用名: NRF3

关于 NFE2L3

功能概要

该基因编码 cap 'n' collar 碱性区亮氨酸拉链转录因子家族的成员。编码的蛋白质与小的肌肉腱膜纤维肉瘤因子异二聚化，以结合靶基因中的抗氧化反应元件。这种蛋白质是一种膜结合糖蛋白，靶向内质网和核膜。在 16、17 和 18 号染色体上发现了该基因的假基因。[RefSeq 提供，2009 年 3 月]

This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]