2. Gene
  3. TM9SF4 - transmembrane 9 superfamily member 4 Gene

TM9SF4 - transmembrane 9 superfamily member 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜 9 超家族成员 4

种属: Homo sapiens

同用名: dJ836N17.2

基因 ID: 9777 | 基因类型: protein coding

关于 TM9SF4

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:32,109,714-32,167,256 (from NCBI)

This gene has 7 transcripts (splice variants), 213 orthologues and 3 paralogues. Ubiquitous expression in placenta (RPKM 20.7), brain (RPKM 16.4) and 25 other tissues.

功能概要

参与多个过程，包括蛋白质定位的正调节；调节细胞内 pH 值；和液泡质子传输 V 型 ATP 酶复合物组装。位于高尔基体和早期核内体。 [由基因组资源联盟提供，2022 年 4 月]

Involved in several processes, including positive regulation of protein localization; regulation of intracellular pH; and vacuolar proton-transporting V-type ATPase complex assembly. Located in Golgi apparatus and early endosome. [provided by Alliance of Genome Resources, Apr 2022]

TM9SF4 基因产物(2)

mRNA Protein Name
NM_001363731.2 NP_001350660.1 transmembrane 9 superfamily member 4 isoform 2
NM_014742.4 NP_055557.2 transmembrane 9 superfamily member 4 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25659576 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion IMP
IMP: 通过突变表型推断
25961573 GOA
involved in phagocytosis IMP
IMP: 通过突变表型推断
19893578 GOA
involved in positive regulation of protein exit from endoplasmic reticulum IMP
IMP: 通过突变表型推断
25999474 GOA
involved in positive regulation of protein localization to cell surface IMP
IMP: 通过突变表型推断
25999474 GOA
involved in regulation of intracellular pH IMP
IMP: 通过突变表型推断
19893578 GOA
involved in response to hypoxia IDA
IDA: 通过直接分析推断
25961573 GOA
involved in vacuolar proton-transporting V-type ATPase complex assembly IMP
IMP: 通过突变表型推断
25659576 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
25999474 GOA
located in early endosome IDA
IDA: 通过直接分析推断
19893578 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TM9SF4 蛋白结构

EMP70

EMP70: Endomembrane protein 70 (54 - 600)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 642 a.a.
蛋白主名 其他名称

transmembrane 9 superfamily member 4

dinucleotide oxidase disulfide thiol exchanger 3 superfamily member 4

TM9SF4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TM9SF4 Q92544 MTOR Homo sapiens P42345
Anti Bait CoIP
29125601
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14615 TM9SF4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus TM9SF4 VGNC VGNC:66230
Canis familiaris TM9SF4 VGNC VGNC:47417
Bos taurus TM9SF4 VGNC VGNC:35913
Rattus norvegicus TM9SF4 RGD RGD:1307768
Macaca mulatta TM9SF4 VGNC VGNC:79883
Mus musculus TM9SF4 MGD MGI:2139220
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z