2. Gene
  3. RNF10 - ring finger protein 10 Gene

RNF10 - ring finger protein 10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：无名指蛋白 10

种属: Homo sapiens

同用名: RIE2

基因 ID: 9921 | 基因类型: protein coding

关于 RNF10

Cytogenetic location: 12q24.31 Genomic coordinates (GRCh38): 12:120,534,356-120,577,588 (from NCBI)

This gene has 25 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in testis (RPKM 52.4), bone marrow (RPKM 51.8) and 25 other tissues.

功能概要

该基因编码的蛋白质包含无名指基序，已知该基序参与蛋白质-蛋白质相互作用。这种蛋白质的具体功能尚未确定。 EST 数据表明存在多个选择性剪接的转录本变体，但是，它们的全长性质尚不清楚。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene contains a ring finger motif, which is known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. EST data suggests the existence of multiple alternatively spliced transcript variants, however, their full length nature is not known. [provided by RefSeq, Jul 2008]

RNF10 基因产物(2)

mRNA Protein Name
NM_001330474.2 NP_001317403.1 RING finger protein 10 isoform 2
NM_014868.5 NP_055683.3 RING finger protein 10 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16335786 GOA
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
24105792 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
16335786 GOA
involved in protein autoubiquitination IDA
IDA: 通过直接分析推断
24105792 GOA
involved in protein monoubiquitination IDA
IDA: 通过直接分析推断
34348161 GOA
involved in ribosome-associated ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
34348161 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16335786 GOA
is active in cytosolic ribosome IDA
IDA: 通过直接分析推断
34348161 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RNF10 蛋白结构

zf-C3HC4_2

zf-C3HC4_2: Zinc finger, C3HC4 type (RING finger) (225 - 266)

  • 0
  • 200
  • 400
  • 600
  • 811 a.a.
蛋白主名 其他名称

RING finger protein 10

epididymis secretory sperm binding protein

RNF10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra RNF10 Q8N5U6 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra RNF10 Q8N5U6 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra RNF10 Q8N5U6 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 DMWD Homo sapiens G5E9A7
Validated Y2H
32814053
Intra RNF10 Q8N5U6 DMWD Homo sapiens G5E9A7
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 DMWD Homo sapiens G5E9A7
Y2H Array
32814053
Intra RNF10 Q8N5U6 CLSTN1 Homo sapiens O94985-2
Validated Y2H
32814053
Intra RNF10 Q8N5U6 CLSTN1 Homo sapiens O94985-2
Y2H Array
32814053
Intra RNF10 Q8N5U6 CLSTN1 Homo sapiens O94985-2
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 LAMP2 Homo sapiens P13473-2
Validated Y2H
32814053
Intra RNF10 Q8N5U6 LAMP2 Homo sapiens P13473-2
Y2H Array
32814053
Intra RNF10 Q8N5U6 LAMP2 Homo sapiens P13473-2
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 UBE2E3 Homo sapiens Q969T4
Y2H Array
19549727
Intra RNF10 Q8N5U6 HSPB1 Homo sapiens P04792
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 HSPB1 Homo sapiens P04792
Validated Y2H
32814053
Intra RNF10 Q8N5U6 HSPB1 Homo sapiens P04792
Y2H Array
32814053
Intra RNF10 Q8N5U6 YWHAE Homo sapiens P62258
Crosslink
36931259
Intra RNF10 Q8N5U6 RNF11 Homo sapiens Q9Y3C5
Y2H Array
32814053
Intra RNF10 Q8N5U6 RNF11 Homo sapiens Q9Y3C5
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 RNF11 Homo sapiens Q9Y3C5
Validated Y2H
32814053
Intra RNF10 Q8N5U6 HIP1 Homo sapiens O00291
Validated Y2H
32814053
Intra RNF10 Q8N5U6 HIP1 Homo sapiens O00291
Y2H Array
32814053
Intra RNF10 Q8N5U6 HIP1 Homo sapiens O00291
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra RNF10 Q8N5U6 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra RNF10 Q8N5U6 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 TERF1 Homo sapiens P54274
Pull Down
21044950
Intra RNF10 Q8N5U6 CASP6 Homo sapiens P55212
Y2H Array
32814053
Intra RNF10 Q8N5U6 CASP6 Homo sapiens P55212
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 CASP6 Homo sapiens P55212
Validated Y2H
32814053
Intra RNF10 Q8N5U6 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra RNF10 Q8N5U6 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra RNF10 Q8N5U6 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 UBE2D1 Homo sapiens P51668
Y2H Array
19549727
Intra RNF10 Q8N5U6 UBE2D1 Homo sapiens P51668
Y2H
19549727
Intra RNF10 Q8N5U6 UBE2D4 Homo sapiens Q9Y2X8
Y2H Array
19549727
Intra RNF10 Q8N5U6 COQ8A Homo sapiens Q8NI60
Validated Y2H
32814053
Intra RNF10 Q8N5U6 COQ8A Homo sapiens Q8NI60
Y2H Pooling
32814053
Intra RNF10 Q8N5U6 COQ8A Homo sapiens Q8NI60
Y2H Array
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Superficial Keratitis
Leukodystrophy, Hypomyelinating, 2

Pmld1

Hypomyelinating Leukodystrophy 2

HLD2

Pelizaeus-Merzbacher-Like Disease 1

Pelizaeus-Merzbacher-Like Disease Due To Gjc2 Mutation

Pelizaeus-Merzbacher-Like Disease Type 1

Pelizaeus-Merzbacher-Like Disease, 1

Pelizaeus Merzbacher Like Disease

Pelizaeus-Merzbacher-Like Disease

Pmld - Pelizaeus Merzbacher Like Disease

Pelizaeus-Merzbacher-Like Disease Autosomal Recessive Type 1

Pmldar1

Leukodystrophy, Hypomyelinating, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12034 RNF10 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RNF10 MGD MGI:1859162
Canis familiaris RNF10 VGNC VGNC:97218
Bos taurus RNF10 VGNC VGNC:34007
Rattus norvegicus RNF10 RGD RGD:1309282
Macaca mulatta RNF10 VGNC VGNC:76702
Others RNF10 NCBI
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