2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. hCAII-IN-10

hCAII-IN-10 (compound 11d) 为 hCAII 抑制剂，对 hCAII 和 hCAI 的 IC50s 分别为 14 nM 和 29.2 μM。hCAII-IN-10 对 HT-29 细胞具有抑制作用，IC50 值为 74 μM。hCAII-IN-10 降低青光眼兔眼模型眼压。

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hCAII-IN-10 Chemical Structure

hCAII-IN-10 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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hCAII-IN-10 相关抗体

Top Publications Citing Use of Products

查看 Carbonic Anhydrase 亚型特异性产品:

查看所有亚型
CA CA I CA Ⅱ CA Ⅸ CA XII

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hCAII-IN-10 (compound 11d) is hCA II inhibitor with the IC50s of 14 nM and 29.2 μM for hCA II and hCA I, respectively. hCAII-IN-10 inhibits cell growth against HT-29 cells with the IC50 of 74 μM. hCAII-IN-10 shows strongly lowered intraocular pressure in the glaucomatous rabbit eye model[1].

IC50 & Target

hCA II

14 nM (IC50)

hCA I

29.2 μM (IC50)

分子量

391.40

Formula

C13H21N5O7S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

hCAII-IN-10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hCAII-IN-10Carbonic AnhydraseCarbonate dehydrataseHT-29 cellsthe glaucomatous rabbit eye modelInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-161282
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