Carbonic Anhydrase Inhibitors

CA I

CA Ⅱ

CA Ⅸ

CA XII

Carbonic Anhydrase Inhibitors & Activators

Product Name	CA	CA I	CA Ⅱ	CA Ⅸ	CA XII	Purity
Acetazolamide				CA Ⅸ		99.89%
U-104				CA Ⅸ	CA XII	99.95%
Methazolamide			CA Ⅱ			99.43%
Girentuximab				CA Ⅸ		99.90%
Zonisamide			CA Ⅱ			99.85%
Acetazolamide sodium				CA Ⅸ		99.66%
Dorzolamide hydrochloride			CA Ⅱ			99.92%
Benzolamide			CA Ⅱ			99.07%
Furagin				hCA IX, Ki: 260 nM	hCA XII, Ki: 57 nM	99.84%
Acetazolamide (Standard)				CA Ⅸ		99.69%
Carbonic anhydrase inhibitor 2			CA Ⅱ			98.40%
hCAIX-IN-18		hCA I, IC₅₀: 3.5 nM	hCA II, IC₅₀: 9.4 nM	hCA IX, IC₅₀: 43 nM	hCA XII, IC₅₀: 8.2 nM	98.52%
Procodazole				CA Ⅸ, IC₅₀: 8.35 μM		99.73%
EMAC10101d			CA Ⅱ			99.77%
Enpp/Carbonic anhydrase-IN-1			CA Ⅱ, IC₅₀: 0.88 μM	CA Ⅸ, IC₅₀: 1.02 μM		99.57%
Carbonic anhydrase/AChE-IN-1		hCA I, Ki: 24.42 nM	hCA II, Ki: 19.95 nM
Phenylsulfamide			hCA II, Kd: 45.50 μM hCA II, Ki: 79.60 μM
Carbonic anhydrase inhibitor 12			CA Ⅱ
hCAI/II-IN-8		hCA I, IC₅₀: 21.35 nM	hCA II, IC₅₀: 7.12 nM
COX-2-IN-30		hCA I, Ki: 183.4 nM	hCA II, Ki: 81.4 nM	hCA IX, Ki: 38.4 nM	hCA XII, Ki: 21.6 nM
hCAII-IN-5			hCA II, IC₅₀: 4.55 μM
hCAIX-IN-19				hCA IX, Ki: 6.2 nM
hCAIX/XII-IN-9		hCA I, Ki: 1658 nM	hCA II, Ki: 184.8 nM	hCA IX, Ki: 8.9 nM	hCA XII, Ki: 64.8 nM
hCAII-IN-4			hCA II, IC₅₀: 7.78 μM
hCAII-IN-8			hCA II, IC₅₀: 0.18 μM			99.41%
hCAIX-IN-24				hCA IX, Ki: 32.1 nM	hCA XII, Ki: 8.1 nM
hCAIX-IN-12				CA Ⅸ
hCAII-IN-3			CA Ⅱ	CA Ⅸ	CA XII
Lasamide				hCA IX, Ki: 2.67 nM	hCA XII, Ki: 7.54 nM
hCAIX/XII-IN-7		hCA I, Ki: 503.7 nM	hCA II, Ki: 59 nM	hCA IX, Ki: 3.2 nM	hCA XII, Ki: 9.2 nM
hCAII-IN-9			hCA II, IC₅₀: 1.18 μM	hCA IX, IC₅₀: 0.17 μM	hCA XII, IC₅₀: 2.99 μM
hCAIX-IN-17			CA Ⅱ	CA Ⅸ	CA XII
GZ22-4			CA Ⅱ, Kd: 200 nM	CA Ⅸ, Kd: 0.2 nM	CA XII, Kd: 80 nM
hCAIX-IN-15				hCA IX, Ki: 38.8 nM
HCAIX-IN-2		CA I, Ki: 2481 nM	hCA II, Ki: 456.2 nM	hCA IX, Ki: 24.6 nM	hCA XII, Ki: 45.3 nM
hCAIX/XII-IN-5				hCA IX, Ki: 93.9 nM	hCA XII, Ki: 85.7 nM
hCAIX/XII-IN-8		hCA I, Ki: 5269 nM	hCA II, Ki: 72.0 nM	hCA IX, Ki: 8.5 nM	hCA XII, Ki: 6.7 nM
Enpp/Carbonic anhydrase-IN-2				CA Ⅸ, IC₅₀: 0.33 μM	CA XII, IC₅₀: 0.68 μM	99.76%
hCA I-IN-3		hCA I, IC₅₀: 4.77 nM	hCA II, IC₅₀: 9.66 nM
VM4-037				CA Ⅸ
Carbonic anhydrase inhibitor 20		hCA I, Ki: 47.6 nM ([1])	hCA II, Ki: 36.5 nM ([1])	hCA IX, Ki: 8.3 nM ([1])	hCA XII, Ki: 2.7 nM ([1])
DTP348				CA Ⅸ, Ki: 8.3 nM
hCAIX-IN-6					CA XII
CA/MAO-B-IN-1	hCA VB, IC₅₀: 8.8 nM hCA VA, IC₅₀: 9.6 nM	hCA I, IC₅₀: 553.1 nM	hCA II, IC₅₀: 41.1 nM		hCA XII, IC₅₀: 196 nM	98.34%
CA IX-IN-2			CA Ⅱ, IC₅₀: 430 nM	CA Ⅸ, IC₅₀: 5.6 nM	CA XII, IC₅₀: 7.4 nM
hCAXII-IN-1				CA Ⅸ
β-Glucuronidase/hCAII-IN-2			hCA II, IC₅₀: 21.77 μM
ALP/Carbonic anhydrase-IN-1			CA Ⅱ, IC₅₀: 0.44 μM	CA Ⅸ, IC₅₀: 1.61 μM	CA XII, IC₅₀: 0.51 μM	99.90%
CAIX/CAXII-IN-2				hCA IX, Ki: 8.9 nM	hCA XII, Ki: 5.3 nM
Dorzolamide hydrochloride (Standard)			CA Ⅱ
Acetazolamide-¹³C₂,d₃				CA Ⅸ
hCAIX/XII-IN-6			hCA II, Ki: 2950 nM	hCA IX, Ki: 4.1 nM	hCA XII, Ki: 7.7 nM
CA IX/VEGFR-2-IN-2				CA Ⅸ, Ki: 3.1 μM
HCAIX-IN-1		hCA I, Ki: 694.9 nM	hCA II, Ki: 126.6 nM	hCA IX, Ki: 3.3 nM	hCA XII, Ki: 9.8 nM
hCAIX-IN-21		hCA I, Ki: 13600 nM	hCA II, Ki: 3.5 nM	hCA IX, Ki: 5.2 nM	hCA XII, Ki: 12.6 nM
BChE-IN-36	hCA VB, KA: 893 nM	hCA I, KA: 266 nM	hCA II, KA: 76.9 nM
hCAIX-IN-14				hCA IX, Ki: 134.8 nM
α-Glucosidase-IN-63			hCA II, Ki: 7.0 nM	hCA IX, Ki: 64.1 nM	hCA XII, Ki: 19.9 nM
Carbonic anhydrase inhibitor 10				CA Ⅸ
hCAIX-IN-23				hCA IX, Ki: 10.4 nM	hCA XII, Ki: 8.5 nM
hCAIX/XII-IN-11				hCA IX, Ki: 0.7 μM	hCA XII, Ki: 0.7 μM
Carbonic anhydrase inhibitor 14		hCA I, Ki: 1203 nM	hCA II, Ki: 99.7 nM	hCA IX, Ki: 9.4 nM	hCA XII, Ki: 27.7 nM
hCAXII-IN-9		hCA I, Ki: 7192.6 nM	hCA II, Ki: 188.6 nM	hCA IX, Ki: >100000 nM	hCA XII, Ki: 28 nM
Methazolamide-d₆			CA Ⅱ
hCA/VEGFR-2-IN-5				hCA IX, IC₅₀: 40 nM	hCA XII, IC₅₀: 3.2 nM
Carbonic anhydrase inhibitor 3			CA Ⅱ
hCAIX-IN-22					hCA XII, Ki: 9.7 nM
AChE/CA I-IN-1		hCA I, Ki: 0.53 μM
Carbonic anhydrase inhibitor 9			CA Ⅱ	CA Ⅸ
CAIX/CAXII-IN-1			CA Ⅱ	CA Ⅸ	CA XII
CA Ⅱ-IN-1			hCA II, : 0.44 μM
hCAII-IN-10		hCA I, IC₅₀: 29.2 μM	hCA II, IC₅₀: 14 nM
DPP IV/hCA II-IN-1		CA I, Ki: 0.2615 μM	CA Ⅱ, IC₅₀: 36.1 nM hCA II, Ki: 0.0361 μM	hCA IX, Ki: 0.1328
Brinzolamide hydrochloride			hCA II, IC₅₀: 3.2 nM
CAII-IN-3			bovine CA-II, IC₅₀: 13.4 μM
hCAIX/XII-IN-1				CA Ⅸ
β-Glucuronidase/hCAII-IN-1			hCA II, IC₅₀: 4.91 μM
Dorzolamide-d₅			CA Ⅱ
Carbonic anhydrase inhibitor 19		hCA I, IC₅₀: 49.1 nM	hCA II, IC₅₀: 9.4 nM	hCA IX, IC₅₀: 4.7 nM	hCA XII, IC₅₀: 6.7 nM
L-662583			hCA II, IC₅₀: 0.7 nM
Carbonic anhydrase inhibitor 25		hCA I	hCA II
hCAI/II-IN-7	bovine CA, Ki: 20.57 μM	hCA I, Ki: 23 nM	hCA II, Ki: 44 nM

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