1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase
  3. hCAIX-IN-21

hCAIX-IN-21 (compound 16c) 是一种有效的 hCAIX 抑制剂,对 hCAIX、hCA II、hCA XII 和 hCA I 的 KI 值分别为 5.2、3.5、12.6、13600 nM。hCAIX-IN-21 可抑制组织蛋白酶 B 酶活性。

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hCAIX-IN-21 Chemical Structure

hCAIX-IN-21 Chemical Structure

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查看 Carbonic Anhydrase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hCAIX-IN-21 (compound 16c) is a potent hCAIX inhibitor with KI values of 5.2, 3.5, 12.6, 13600 nM for hCAIX, hCA II, hCA XII, hCA I, respectively. hCAIX-IN-21 inhibits cathepsin B enzyme activity[1].

IC50 & Target[1]

hCA IX

5.2 nM (Ki)

hCA II

3.5 nM (Ki)

hCA XII

12.6 nM (Ki)

hCA I

13600 nM (Ki)

分子量

456.45

Formula

C20H17FN6O4S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
hCAIX-IN-21
目录号:
HY-159128
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