1. Anti-infection
  2. HIV
  3. HIV gp120 (318-327)

HIV gp120 (318-327) 是 HIV-1 IIIB 株系包膜肽的一段短序列 (rgpgrafvti),对应糖蛋白的保守 C 端区域。HIV gp120 (318-327) 是 HIV 疫苗 V3 肽表位的一部分,也称为 I10 肽。但 HIV gp120 (318-327) 缺乏与表位特异性 CTL 识别的 A2 锚定残基,但具有赋予混杂 A2 结合的结构特征。

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Custom Peptide Synthesis

HIV gp120 (318-327) Chemical Structure

HIV gp120 (318-327) Chemical Structure

CAS No. : 147841-68-7

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生物活性

HIV gp120 (318-327) is a short sequence of the HIV-1 strain IIIB envelope peptide (rgpgrafvti) that corresponds to the conserved C-terminal region of the glycoprotein. HIV gp120 (318-327) is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIV gp120 (318-327) lacks the A2 anchor residues recognized by epitope-specific CTLs but has structural features that confer promiscuous A2 binding[1][2].

体外研究
(In Vitro)

HIV gp120 (318-327) (0.5 μM) 刺激表达 7DV3 突变体的 JA2 细胞中 CTL 反应减弱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1073.25

Formula

C48H80N16O12

CAS 号
Sequence

Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile

Sequence Shortening

RGPGRAFVTI

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HIV gp120 (318-327)
目录号:
HY-P10251
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