2. Epigenetics
  3. MicroRNA
  4. hsa-miR-378i agomir

hsa-miR-378i agomir 是一种经过特殊化学修饰的miRNA模拟物，miRNA成熟链全链进行甲氧基修饰，在5'端和3'端分别有2个和4个硫代骨架修饰，并在3'端连接有高亲和性胆固醇修饰。miRNA agomir 可以模拟内源性miRNA，上调miRNA活性。与普通模拟物相比，miRNA agomir在动物实验中具有更高的稳定性和抑制效果，更易通过细胞膜、组织间隙而富集于靶细胞。

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RNA, (ACUGGACUAGGAGUCAGAAGG), complex with RNA, (UUCUGACUCCUAGUCCAGUNN) (1:1) (with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

hsa-miR-378i agomir Chemical Structure

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3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 nmol ￥1580
1-2 weeks
20 nmol ￥3160
1-2 weeks

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Customer Review

Other Forms of hsa-miR-378i agomir:

hsa-miR-378i agomir 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

hsa-miR-378i agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

分子量

14533.02

miRBase编号
成熟miRNA序列

ACUGGACUAGGAGUCAGAAGG

茎环结构ID

hsa-mir-378i

茎环结构序列

GGGAGCACUGGACUAGGAGUCAGAAGGUGGAGUUCUGGGUGCUGUUUUCCCACUCUUGGGCCCUGGGCAUGUUCUG

种属

Human

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

hsa-miR-378i agomir 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hsa-miR-378i agomirMicroRNAmiRNAInhibitorinhibitorinhibit

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产品名称：
hsa-miR-378i agomir
目录号：
HY-R00852A
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