2. Apoptosis
  3. Apoptosis
  4. Isoharringtonine

Isoharringtonine 是一种天然生物碱，可以从 Cephalotaxus koreana Nakai 中纯化得到。Isoharringtonine 能抑制癌细胞的增殖和迁移，并诱导癌细胞凋亡 (apoptosis)。Isoharringtonine 可用于癌症的研究。

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Isoharringtonine Chemical Structure

Isoharringtonine Chemical Structure

CAS No. : 26833-86-3

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Isoharringtonine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Isoharringtonine is a natural alkaloid that can be purified from Cephalotaxus koreana Nakai. Isoharringtonine can inhibit cancer cell proliferation and migration, and induce cancer cell apoptosis. Isoharringtonine can be used for the research of cancers[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCC1806 IC50
100 nM
Compound: 31; IHT
Anticancer activity against human HCC1806 cells assessed as cell growth inhibition incubated for 24 hrs by MTS assay
Anticancer activity against human HCC1806 cells assessed as cell growth inhibition incubated for 24 hrs by MTS assay
[PMID: 33650861]
HCC1937 IC50
500 nM
Compound: 31; IHT
Anticancer activity against human HCC1937 cells assessed as cell growth inhibition incubated for 24 hrs by MTS assay
Anticancer activity against human HCC1937 cells assessed as cell growth inhibition incubated for 24 hrs by MTS assay
[PMID: 33650861]
分子量

531.59

Formula

C28H37NO9
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Isoharringtonine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isoharringtonine26833-86-3ApoptosisNSCLCcancerbreast cancerInhibitorinhibitorinhibit

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