1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. Lipopolysaccharides, from E. coli O127:B8

Lipopolysaccharides, from E. coli O127:B8  (Synonyms: LPS, from Escherichia coli (O127:B8))

目录号: HY-D1056A2
产品使用指南

Lipopolysaccharides, from E. coli O127:B8 是一种来源于大肠杆菌 O127:B8脂多糖内毒素和 TLR-4 激活剂,可激活免疫系统的致病相关分子模式 (PAMP) 和诱导细胞分泌迁移体。Lipopolysaccharides, from E. coli O127:B8 由一个抗原 O-特异性链、一个核心寡糖和脂质 A 构成。Lipopolysaccharides, from E. coli O127:B8 可以引起大鼠体温变化且具有剂量和血清型特异性具有剂量和血清型特异性,高剂量 Lipopolysaccharides, from E. coli O127:B8 可引起了大鼠体温的双重变化,即先出现低体温然后是发热。此外,Lipopolysaccharides, from E. coli O127:B8 具有炎症诱导与生殖抑制作用,并可导致软体动物有丝分裂活性大幅度增加。

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Lipopolysaccharides, from E. coli O127:B8 Chemical Structure

Lipopolysaccharides, from E. coli O127:B8 Chemical Structure

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规格 价格 是否有货 数量
5 mg ¥1400
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10 mg ¥2300
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查看 Toll-like Receptor (TLR) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lipopolysaccharides, from E. coli O127:B8 is a lipopolysaccharide endotoxin from E. coli O127:B8 and TLR-4 activator, Activates disease-associated molecular patterns (PAMPs) of the immune system and induces cell secretion of migratory bodies. Lipopolysaccharides, from E. coli O127:B8 consists of an antigen-specific O-chain, A core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O127:B8 can induce changes in body temperature in rats and is dose and serotype specific. High dose of Lipopolysaccharides, from E. coli O127:B8 can cause a double change of body temperature in rats, that is, hypothermia followed by fever. In addition, Lipopolysaccharides, from E. coli O127:B8 can induce inflammation and inhibit reproduction, and can significantly increase the mitotic activity of mollusks[1][2][3][4][5][6][7].

IC50 & Target

TLR-4[2]

中文名称

脂多糖,来源于大肠杆菌O127:B8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lipopolysaccharides, from E. coli O127:B8
目录号:
HY-D1056A2
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