2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. Drug-Linker Conjugates for ADC Topoisomerase
  4. MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan 

目录号: HY-148668A 纯度: 95.11%
COA 产品使用指南

摩尔计算器

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan 是抗体偶联活性分子的一部分 (drug-linker conjugate for ADC)，包含 Exatecan (HY-13631)。Exatecan 是一种 DNA 拓扑异构酶 I (Topoisomerase I) 抑制剂 (IC50=2.2 μM)。

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MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Chemical Structure

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan Chemical Structure

CAS No. : 2414254-52-5

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规格 价格 是否有货 数量
1 mg ￥7500
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Other Forms of MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan:

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan 相关抗体

Top Publications Citing Use of Products

查看 Drug-Linker Conjugates for ADC 亚型特异性产品:

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

IC50 & Target[1]

Camptothecins

 

分子量

1074.12

Formula

C55H60FN9O13
CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan2414254-52-5Drug-Linker Conjugates for ADCTopoisomeraseInhibitorinhibitorinhibit

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产品名称：
MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
目录号：
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