Docking for EP4R antagonists active against inflammatory pain

Affiliations

• 1 Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA.
• 2 Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27514, USA.
• 3 Department of Anatomy, University of California San Francisco, San Francisco, CA, 94158, USA.
• 4 Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
• 5 Center of Clinical Pharmacology, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
• 6 Enamine Ltd., Kyiv, Ukraine.
• 7 V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine.
• 8 Chemspace LLC, Kyiv, Ukraine.
• 9 National Taras Shevchenko University of Kyiv, Kyiv, Ukraine.
• 10 Department of Anatomy, University of California San Francisco, San Francisco, CA, 94158, USA. allan.basbaum@ucsf.edu.
• 11 Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27514, USA. bryan_roth@med.unc.edu.
• 12 National Institute of Mental Health Psychoactive Drug Screening Program, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27514, USA. bryan_roth@med.unc.edu.
• 13 Division of Chemical Biology and Medicinal Chemistry, University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, NC, 27514, USA. bryan_roth@med.unc.edu.
• 14 Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA. bshoichet@gmail.com.
• # Contributed equally.