Lactylation of HDAC1 Confers Resistance to Ferroptosis in Colorectal Cancer

Affiliations

• 1 Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
• 2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
• 3 Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
• 4 Departments of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Nanjing Medical University, Nanjing, Jiangsu, 214043, China.
• 5 Department of Integrative Medicine, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
• 6 Department of Medical Oncology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China.
• 7 Department of General Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine; National Experimental Teaching Center of Basic Medical Science, Department of Medical Genetics, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.
• 8 Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
• 9 Department of Immunology, Key Laboratory of Immune Microenvironment and Disease, The School of Basic Medicine; Department of laboratory medicine, the first affiliated hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, 211166, China.
• 10 State Key Laboratory Cultivation Base of Biomarkers for Cancer Precision Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine; NHC Key Laboratory of Antibody Technique, Jiangsu Province Engineering Research Center of Antibody Drug, Nanjing Medical University, Nanjing, 211166, China.