CD204/MSR1 蛋白, Mouse (HEK293, His)

CD204/MSR1 Protein, a membrane glycoprotein, crucially contributes to cholesterol accumulation in arterial walls during atherogenesis. With two receptor subunits, it facilitates endocytosis of various macromolecules, including modified low-density lipoproteins (LDL). As a homotrimer, CD204/MSR1 engages in key interactions, including its association with MYO18A, highlighting its functional role in cellular processes. CD204/MSR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD204/MSR1 protein, expressed by HEK293 , with N-His labeled tag.

CD204/MSR1 蛋白是一种膜糖蛋白，在动脉粥样硬化形成过程中动脉壁胆固醇的病理性积累中发挥着至关重要的作用。该蛋白质由两种类型的受体亚基组成，促进多种大分子的内吞作用，包括修饰的低密度脂蛋白 (LDL)。作为同源三聚体，CD204/MSR1 参与关键的相互作用，例如与 MYO18A 的关联，有助于其在细胞过程中的功能作用。

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse CD204 at 5 µg/mL (100 µL/well) can bind biotinylated advanced glycation endproducts of bovine serum albumin (AGE-BSA). The ED₅₀ for this effect is 92.81 ng/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse CD204 at 5 µg/mL (100 µL/well) can bind biotinylated advanced glycation endproducts of bovine serum albumin (AGE-BSA) .The ED₅₀ for this effect is 92.81 ng/mL

Mouse

HEK293

N-His

AAH03814.1 (W83-V354)

20288  [NCBI]

WEMKNCLVCSLNTSDTSQGPMEKENTSKVEMRFTIIMEHMKDMEERIESISNSKADLIDTERFQNFSMATDQRLNDILLQLNSLISSVQEHGNSLDAISKSLQSLNMTLLDVQLHTETLNVRVRESTAKQQEDISKLEERVYKVSAEVQSVKEEQAHVEQEVKQEVRVLNNITNDLRLKDWEHSQTLKNITFIQGPPGPQGEKGDRGLTGQTGPPGAPGIRGIPGVKGDRGQIGFPGGRGNPGAPGKPGRSGSPGPKGQKGEKGSVGGSRSV

Approximately 42-75 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.