CRABP1 蛋白, Human

The CRABP1 protein is present in the cytoplasm and is involved in regulating the entry of retinoic acid into nuclear retinoic acid receptors. As an important molecular player, CRABP1 may mediate the complex process of interaction between retinoic acid and its nuclear receptor. CRABP1 Protein, Human is the recombinant human-derived CRABP1 protein, expressed by E. coli , with tag free. The total length of CRABP1 Protein, Human is 137 a.a., with molecular weight of ~14 kDa.

细胞视黄酸结合蛋白 1 (CRABP1) 是一种胞质蛋白，已知在调节视黄酸进入核视黄酸受体方面发挥作用。作为细胞视黄酸结合蛋白家族的一部分，CRABP1 参与细胞内视黄酸代谢和信号传导。具体来说，它的胞质位置表明它可能充当控制视黄酸对核视黄酸受体的可用性的介质，影响视黄酸信号传导的下游效应。这种调节功能强调了 CRABP1 在调节细胞对视黄酸反应中的重要性，视黄酸是参与各种生理过程（包括发育和分化）的关键信号分子。

Human

E. coli

Tag Free

AAH22069.1 (M1-E137)

1381  [NCBI]

MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKVGEGFEEETVDGRKCRSLATWENENKIHCTQTLLEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE

Approximately 14 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0, 10% Glycerol.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.