DPEP1 蛋白, Human (HEK293, His)

Dipeptidase 1 (DPEP1) has multiple enzymatic functions and can hydrolyze various dipeptides, including the conversion of leukotriene D4 to leukotriene E4. It is also involved in the degradation of cysteinylbisglycine resulting from the breakdown of glutathione. DPEP1 Protein, Human (HEK293, His) is the recombinant human-derived DPEP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DPEP1 Protein, Human (HEK293, His) is 369 a.a., with molecular weight of ~41.0 kDa.

二肽酶 1 (DPEP1) 具有多种酶功能，可水解多种二肽，包括将白三烯 D4 转化为白三烯 E4。此外，它还在谷胱甘肽分解过程中形成的胱氨酰双甘氨酸的降解中发挥作用。值得注意的是，DPEP1 表现出 β 内酰胺酶活性，能够水解 β-内酰胺抗生素亚胺培南。除了其酶促功能外，DPEP1 还充当粘附受体，促进中性粒细胞从血流募集到发炎的肺部和肝脏，而与其二肽酶活性无关。

Human

HEK293

C-6*His

P16444 (D17-S385)

1800  [NCBI]

DFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSS

Approximately 41.0 kDa

Greater than 95% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.