INPP5A 蛋白, Human (HEK293, His)

INPP5A Protein, a phosphatase, catalyzes the hydrolysis of inositol phosphates, converting inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. This enzymatic action underscores its role in inositol phosphate metabolism. INPP5A is crucial for the survival of cerebellar Purkinje cells, emphasizing its significance in cellular processes and neuronal function. INPP5A Protein, Human (HEK293, His) is the recombinant human-derived INPP5A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of INPP5A Protein, Human (HEK293, His) is 410 a.a., with molecular weight of ~48.0 kDa.

INPP5A蛋白是一种具有特定酶活性的磷酸酶，催化肌醇1,4,5-三磷酸的5-磷酸水解为肌醇1,4-二磷酸，以及肌醇1,3,4,5-四磷酸水解为肌醇1 ,3,4-三磷酸。这种酶促作用突出了其在磷酸肌醇代谢中的作用。值得注意的是，INPP5A 在小脑浦肯野细胞的存活中发挥着至关重要的作用，强调了它在细胞过程和神经元功能中的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

Q14642 (M1-V410)

3632  [NCBI]

MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGKPHAHVHKCCV

Approximately 48.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.