2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. SAM-315

SAM-315 (WAY-255315) 是 5-羟色胺-6 (5-Hydroxytryptamine-6) 的有效拮抗剂，其 Ki 和 IC50 分别为 1.1 nM 和 4.6 nM。SAM-315 可显著增加大脑海马中乙酰胆碱和谷氨酸的释放。

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SAM-315 Chemical Structure

SAM-315 Chemical Structure

CAS No. : 744218-85-7

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SAM-315 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SAM-315 (WAY-255315) is a potent antagonist of 5-Hydroxytryptamine-6, with Ki and IC50 of 1.1 nM and 4.6 nM, respectively. SAM-315 significantly increases acetylcholine and glutamate release in hippocampus of the brain[1].

IC50 & Target

5-HT6 Receptor

4.6 nM (IC50)

分子量

392.47

Formula

C21H20N4O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SAM-315 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAM-315744218-85-7WAY-255315SAM315SAM 315WAY255315WAY 2553155-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptoracetylcholineInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-14334
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