2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. SB-414796

SB-414796 是一种选择性、具有口服活性且能穿过血脑屏障的多巴胺 D3 (dopamine D3) 受体拮抗剂，对 D3 和 D2 的 Ki 值分别为 4, 400 nM。

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SB-414796 Chemical Structure

SB-414796 Chemical Structure

CAS No. : 264262-71-7

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SB-414796 相关抗体

Top Publications Citing Use of Products

查看 Dopamine Receptor 亚型特异性产品:

查看所有亚型
Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SB-414796 is a selective, orally active and cross the blood-brain barrier dopamine D3 receptor antagonist with Ki values of 4, 400 nM for D3, D2, respectively[1][2].

IC50 & Target[2]

D3 Receptor

4 nM (Ki)

D2 Receptor

400 nM (Ki)

分子量

536.69

Formula

C29H36N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SB-414796 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB-414796264262-71-7SB414796SB 414796Dopamine Receptororally activecross the blood-brain barrierantipsychoticInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-123473
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