2. Cell Cycle/DNA Damage Stem Cell/Wnt Autophagy Cytoskeleton TGF-beta/Smad
  3. ROCK Autophagy
  4. SR-3677 dihydrochloride

SR-3677 dihydrochloride (compound 5) 是一种有效的选择性 ROCK-II 和 ROCK-II 抑制剂，其 IC50 为 56 nM 和 3 nM。

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SR-3677 dihydrochloride Chemical Structure

SR-3677 dihydrochloride Chemical Structure

CAS No. : 1781628-88-3

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SR-3677 dihydrochloride 的其他形式现货产品:

Customer Review

Other Forms of SR-3677 dihydrochloride:

SR-3677 dihydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

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ROCK ROCK1 ROCK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SR-3677 dihydrochloride (compound 5) is a potent and selective ROCK-I and ROCK-II inhibitor with an IC50 values of 56 nM and 3 nM[1].

IC50 & Target

ROCK-I

56 nM (IC50)

ROCK-II

3 nM (IC50)

分子量

481.37

Formula

C22H26Cl2N4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SR-3677 dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SR-36771781628-88-3SR3677SR 3677ROCKAutophagyRho-associated protein kinaseRho-associated kinaseRho-kinaseROKInhibitorinhibitorinhibit

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