2. Anti-infection
  3. SARS-CoV Virus Protease
  4. Tectoquinone

Tectoquinone  (Synonyms: 2-甲基蒽醌; 2-Methylanthraquinone)

目录号: HY-N1739 纯度: 98.21%
COA 产品使用指南

摩尔计算器

Tectoquinone (2-Methylanthraquinone) 是一种针对 COVID-19 的 SARSCoV-2 主要蛋白酶抑制剂。Tectoquinone 具有很强的杀蚊幼虫活性，24 小时内对 A. aegypti 和 A. albopictus 的 LC50 值分别为 3.3 和 5.4 μg/ml。

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Tectoquinone Chemical Structure

Tectoquinone Chemical Structure

CAS No. : 84-54-8

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规格 价格 是否有货 数量
Free Sample (0.1 - 0.2 mg)   Apply now  
10 mM * 1 mL in DMSO ￥110
In-stock
500 mg ￥100
In-stock
1 g ￥160
In-stock
5 g   询价  
10 g   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Tectoquinone:

Tectoquinone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 100 μg/mL
Compound: 4
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 26995526]
ACHN EC50
> 50 μM
Compound: 3
Cytotoxicity against human ACHN cells assessed as cell death after 20 to 24 hrs by XTT assay
Cytotoxicity against human ACHN cells assessed as cell death after 20 to 24 hrs by XTT assay
[PMID: 22313254]
ACHN EC50
> 50 μM
Compound: 3
Cytotoxicity against human ACHN cells assessed as cell death after 20 to 24 hrs by XTT assay in presence of 40 ng/ml TRAIL
Cytotoxicity against human ACHN cells assessed as cell death after 20 to 24 hrs by XTT assay in presence of 40 ng/ml TRAIL
[PMID: 22313254]
CCRF-CEM IC50
> 10 μg/mL
Compound: 5
Cytotoxicity against human CEM cells after 3 days by MTT assay
Cytotoxicity against human CEM cells after 3 days by MTT assay
[PMID: 11421746]
EMT6 ED50
0.54 μM
Compound: 1
Compound is measured for surviving fractions of EMT6 tumor cells treated in culture with (0.50 uM) concentration for 1 hr under hypoxic condition.
Compound is measured for surviving fractions of EMT6 tumor cells treated in culture with (0.50 uM) concentration for 1 hr under hypoxic condition.
[PMID: 7452674]
EMT6 ED50
1.7 μM
Compound: 1
Compound is measured for surviving fractions of EMT6 tumor cells treated in culture with (0.50 uM) concentration for 1 hr under aerobic condition.
Compound is measured for surviving fractions of EMT6 tumor cells treated in culture with (0.50 uM) concentration for 1 hr under aerobic condition.
[PMID: 7452674]
HL-60 IC50
> 10 μg/mL
Compound: 5
Cytotoxicity against human HL60 cells after 3 days by MTT assay
Cytotoxicity against human HL60 cells after 3 days by MTT assay
[PMID: 11421746]
HT-29 IC50
> 100 μg/mL
Compound: 4
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 26995526]
HUVEC IC50
> 100 μg/mL
Compound: 4
Antiproliferative activity against human HUVEC cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human HUVEC cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 26995526]
MCF7 IC50
> 100 μg/mL
Compound: 4
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
[PMID: 26995526]
SW1573 IC50
> 10 μg/mL
Compound: 5
Cytotoxicity against human SW1573 cells after 3 days by MTT assay
Cytotoxicity against human SW1573 cells after 3 days by MTT assay
[PMID: 11421746]
分子量

222.24

Formula

C15H10O2
CAS 号
性状

固体

颜色

Off-white to yellow

中文名称

2-甲基蒽醌
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 12.5 mg/mL (56.25 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.4996 mL 22.4982 mL 44.9964 mL
5 mM 0.8999 mL 4.4996 mL 8.9993 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 98.40%

COA (265 KB) HNMR (130 KB) RP-HPLC (284 KB)

产品使用指南 (1538 KB)
参考文献

Tectoquinone 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4996 mL 22.4982 mL 44.9964 mL 112.4910 mL
5 mM 0.8999 mL 4.4996 mL 8.9993 mL 22.4982 mL
10 mM 0.4500 mL 2.2498 mL 4.4996 mL 11.2491 mL
15 mM 0.3000 mL 1.4999 mL 2.9998 mL 7.4994 mL
20 mM 0.2250 mL 1.1249 mL 2.2498 mL 5.6245 mL
25 mM 0.1800 mL 0.8999 mL 1.7999 mL 4.4996 mL
30 mM 0.1500 mL 0.7499 mL 1.4999 mL 3.7497 mL
40 mM 0.1125 mL 0.5625 mL 1.1249 mL 2.8123 mL
50 mM 0.0900 mL 0.4500 mL 0.8999 mL 2.2498 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tectoquinone84-54-82-Methylanthraquinone2-甲基蒽醌SARS-CoVVirus ProteaseSARS coronavirusSARSCoV-2proteaseCOVID-19mosquito larvicidalA. aegyptiA. albopictusInhibitorinhibitorinhibit

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目录号：
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