2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. aTAG 4531

aTAG 4531  (Synonyms: CFT-4531)

目录号: HY-163168
产品使用指南

摩尔计算器

aTAG 4531 (CFT-4531) 是 MTH1 基于 aTAG 的融合蛋白的有效、选择性和机制工具降解剂。

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aTAG 4531 Chemical Structure

aTAG 4531 Chemical Structure

CAS No. : 2412985-00-1

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aTAG 4531 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

aTAG 4531 (CFT-4531) is a potent, selective, and onmechanism tool degrader of MTH1 with DC50 value of 0.28 nM and Ki value of 1.8 nM. degradation activity is due to the intricate formation of the ternary complex between the MTH1 aTAG, CRBN E3 ligase, and aTAG tool degrader [1].

分子量

867.85

Formula

C46H39F2N9O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

aTAG 4531 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

aTAG 45312412985-00-1CFT-4531aTAG4531aTAG-4531CFT4531CFT 4531DNA/RNA Synthesisonmechanism toolCAR-T cellsInhibitorinhibitorinhibit

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目录号：
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