2. Anti-infection
  3. Beta-lactamase Bacterial Antibiotic
  4. Cefuroxime

Cefuroxime  (Synonyms: 头孢呋辛; Kefurox)

目录号: HY-B1256A 纯度: 99.08%
COA 产品使用指南 技术支持

Cefuroxime 是一种具有口服活性的第二代头孢菌素抗生素 (antibiotic)，增加了对 β-内酰胺酶 (β-lactamase) 的稳定性。Cefuroxime 具有广谱的抑制活性，对革兰氏阳性菌和革兰氏阴性菌都有效。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Cefuroxime Chemical Structure

Cefuroxime Chemical Structure

CAS No. : 55268-75-2

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥264
In-stock
5 mg ￥240
In-stock
10 mg ￥380
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Cefuroxime:

Cefuroxime 相关抗体

Top Publications Citing Use of Products

查看 Beta-lactamase 亚型特异性产品:

查看所有亚型
Metallo-β-lactamase

查看 Antibiotic 亚型特异性产品:

查看所有亚型
Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cefuroxime is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].

IC50 & Target

β-lactam

 

体外研究
(In Vitro)

Cefuroxime is highly active against S. aureus (MIC=0.25 μg/ml), regardless of whether the strains produces a penicillinase. It is against Staphylococcus aureus methicillin susceptible; S. aureus, methicillin resistant, Streptococcus pyogenes, S. pneumoniae, S. viridans, S. faecalis, and Clostridium spp with MIC values of 0.25 μg/ml, 5.9 μg/ml, 0.125 μg/ml, 0.125 μg/ml, 0.125 μg/ml, >125.0 μg/ml, and 1.2 μg/ml, respectively[1].
Cefuroxime (10-100 μg/ml; 2-6 hours) rapidly bactericidal, its action is comparatively slow against the strains of S. aureus, but, even so, over 99% of the initial inoculum is killed by 6 h. The gram-negative organisms are killed rapidly, and in most cases over 99% of the very large inocula are killed within 2 h; the β-lactamase-producing strains are killed as quickly as non-enzyme-producing strains[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cefuroxime 相关抗体:
体内研究
(In Vivo)

Rabbits (weighing 2.0 to 2.5 kg) are challenged intravenously with S. aureus strain 630 (a penicillinase-producing strain), the median effective dose of Cefuroxime is 3 mg/kg as a result of the protection test[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

424.39

Formula

C16H16N4O8S
CAS 号
性状

固体

颜色

White to light yellow

中文名称

头孢呋辛酯EP杂质D
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 116.67 mg/mL (274.91 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3563 mL 11.7816 mL 23.5632 mL
5 mM 0.4713 mL 2.3563 mL 4.7126 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.08%

COA (290 KB) HNMR (287 KB) LCMS (95 KB) 元素分析报告 (213 KB)

产品使用指南 (1538 KB)
参考文献

Cefuroxime 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3563 mL 11.7816 mL 23.5632 mL 58.9081 mL
5 mM 0.4713 mL 2.3563 mL 4.7126 mL 11.7816 mL
10 mM 0.2356 mL 1.1782 mL 2.3563 mL 5.8908 mL
15 mM 0.1571 mL 0.7854 mL 1.5709 mL 3.9272 mL
20 mM 0.1178 mL 0.5891 mL 1.1782 mL 2.9454 mL
25 mM 0.0943 mL 0.4713 mL 0.9425 mL 2.3563 mL
30 mM 0.0785 mL 0.3927 mL 0.7854 mL 1.9636 mL
40 mM 0.0589 mL 0.2945 mL 0.5891 mL 1.4727 mL
50 mM 0.0471 mL 0.2356 mL 0.4713 mL 1.1782 mL
60 mM 0.0393 mL 0.1964 mL 0.3927 mL 0.9818 mL
80 mM 0.0295 mL 0.1473 mL 0.2945 mL 0.7364 mL
100 mM 0.0236 mL 0.1178 mL 0.2356 mL 0.5891 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefuroxime55268-75-2Kefurox头孢呋辛酯EP杂质DBeta-lactamaseBacterialAntibioticβ-lactamaseStaphylococcus aureusS. aureusEscherichia coliStreptococcus pyogenesS. faecalisInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Cefuroxime
目录号：
HY-B1256A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z