2. Neuronal Signaling
  3. Monoamine Oxidase
  4. ChEs/MAOs-IN-1

ChEs/MAOs-IN-1 (Compound 4i) 是胆碱酯酶(ChEs) 和单胺氧化酶 (MAOs) 双重抑制剂. ChEs/MAOs-IN-1 对 AChE、BChE、MAO-B 和 MAO-B 的 IC50 分别为 0.048 μM、0.89 μM、3.58 μM 和0.095 μM。ChEs/MAOs-IN-1 可以用于神经退行性疾病的研究。

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ChEs/MAOs-IN-1 Chemical Structure

ChEs/MAOs-IN-1 Chemical Structure

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ChEs/MAOs-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ChEs/MAOs-IN-1 (Compound 4i) is a dual inhibitor of cholinesterases (ChEs) and monoamine oxidases (MAOs).ChEs/MAOs-IN-1 has IC50 values of 0.048 μM, 0.89 μM, 3.58 μM, and 0.095 μM for AChE, BChE, MAO-B and MAO-B respectively. ChEs/MAOs-IN-1 can be used in the study of neurodegenerative diseases[1].

IC50 & Target

IC50: 0.048 μM (AChE)[1].
IC50: 0.89 μM (BChE)[1].
IC50: 3.58 μM (MAO-A)[1].
IC50: 0.095 μM (MAO-B).[1].
分子量

337.16

Formula

C15H10Cl2N2O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ChEs/MAOs-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ChEs/MAOs-IN-1Monoamine OxidaseMAODual inhibitorsCholinesteraseMonoamine oxidaseHydrazonesNeurodegenerative diseaseDepressionSchizophreniaAlzheimer’s disease (AD)Inhibitorinhibitorinhibit

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