2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. TROP2 ADC Antibody
  4. Datopotamab

Datopotamab  (Synonyms: 德达博妥单抗)

目录号: HY-P99843 纯度: 98.68%
COA

摩尔计算器

Datopotamab (CDP7657) 是一种人源的抗滋养层细胞表面抗原 2 (TROP2) 抗体。Datopotamab 可以与 DNA 拓扑异构酶 I 抑制剂 Deruxtecan (HY-13631E) 生成抗体-药物偶联物 (ADC) Datopotamab deruxtecan (HY-141598)。Datopotamab 可用于三阴性乳腺癌和非小细胞肺癌的研究。

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CAS No. : 2267989-53-5

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥2800
In-stock
5 mg ￥7200
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Customer Review

Datopotamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer[1].
IC50 & Target

TROP2[1]
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

德达博妥单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Datopotamab has a significant ADCC effect on HEK293-HuTrop2 cells in a dose-dependent manner.The EC50 for this effect is 5.75 ng/mL.
纯度 & 产品资料

纯度: 99.00%

COA (264 KB) SDS-PAGE (144 KB) SEC-HPLC (138 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Datopotamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Datopotamab2267989-53-5德达博妥单抗TROP2ADC AntibodyEGP-1M1S1GA733-1Anti-TROP2 antibodyADCtriple negative breast cancernon small cell lung cancerInhibitorinhibitorinhibit

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