2. Gene
  3. IFITM3 - interferon induced transmembrane protein 3 Gene

IFITM3 - interferon induced transmembrane protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：干扰素诱导跨膜蛋白 3

种属: Homo sapiens

同用名: 1-8U; IP15; DSPA2b

基因 ID: 10410 | 基因类型: protein coding

关于 IFITM3

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:319,676-320,860 (from NCBI)

This gene has 27 transcripts (splice variants), 243 orthologues, 4 paralogues and is associated with 1 phenotype. Ubiquitous expression in liver (RPKM 370.9), placenta (RPKM 358.2) and 25 other tissues.

功能概要

干扰素诱导的跨膜 (IFITM) 蛋白是干扰素诱导的抗病毒蛋白家族。该家族包含五个成员，包括 IFITM1、IFITM2 和 IFITM3，属于 CD225 超家族。该基因编码的蛋白质限制多种病毒病原体进入细胞，例如甲型流感病毒、埃博拉病毒和 Sars-CoV-2。[RefSeq 提供，2021 年 11 月]

Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced Antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 and belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2. [provided by RefSeq, Nov 2021]

IFITM3 基因产物(1)

mRNA Protein Name
NM_021034.3 NP_066362.2 interferon-induced transmembrane protein 3

IFITM3 蛋白结构

CD225

CD225: Interferon-induced transmembrane protein (42 - 122)

  • 0
  • 100
  • 133 a.a.
蛋白主名 其他名称

interferon-induced transmembrane protein 3

dispanin subfamily A member 2b

重组 IFITM3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77370 IFITM3/Fragilis Protein, Human (HEK293, Fc) Q01628/NP_066362.2 (M1-H57) ≥95%

关联疾病

疾病名称 别名
Influenza, Severe

Influenza, Severe, Susceptibility To
Influenza

Flu

Influenza With Non-Respiratory Manifestation

Influenza With Other Manifestations

Influenza, Human

Influenza, Susceptibility To

Seasonal Influenza, Virus Identified
Stomatitis
Hepatitis C Virus

Hepatitis C Virus, Susceptibility To

Hepatitis C Virus Infection, Response To Therapy Of

Hcv

Hcv, Susceptibility To

Hepatitis C Virus, Resistance To

Hepatitis C Virus, Response To Therapy Of

Resistance To Hepatitis C Virus
Hepatitis C

Chronic Hepatitis C

Hepatitis C Infection

Hepatitis Nona Nonb

Nanbh

Viral Hepatitis C

Hepatitis C Chronic

Hepatitis C, Chronic

Chronic Type C Viral Hepatitis

Chronic Hcv - [Hepatitis C Virus] Infection

Hepatitis C Nos

Hepatitis C Infection Nos

Hepatitis C-Related Cirrhosis

Type C Viral Hepatitis

Hep C Nos
West Nile Virus

West Nile Virus, Susceptibility To

Wnv

Wnv, Susceptibility To

West Nile Viral Infection

Encephalitis, West Nile Fever

West Nile Fever
Dengue Virus

Dengue Virus, Susceptibility To

Dengue Fever, Protection Against

Dengue Fever
Hepatitis

Chronic Hepatitis

Chronic Persistent Hepatitis

Acute Hepatitis

Hepatitis, Chronic

Acute And Subacute Liver Necrosis

Acute/Subac. Necrosis Of Liver

Animal Hepatitis

Hepatitis Chronic

Hepatitis A

Hepatitis, Animal

Hepatitis Due To Toxoplasmosis

Hepatitis In Toxoplasmosis

Toxoplasmal Hepatitis

Chronic Hepatitis, Unspecified

Chronic Active Hepatitis Nec

Other Specified Chronic Hepatitis

Chronic Persistent Hepatitis Nec

Chronic Lobular Hepatitis Nec
Rift Valley Fever

Rfv - [Rift Valley Fever]
Hand, Foot And Mouth Disease

Vesicular Stomatitis And Exanthem
Chikungunya

Chikungunya Fever

Arbovirus A Chikungunya Type

Chik

Chikv Infection

Ck

Chikungunya Virus Infection

Chikungunya Haemorrhagic Fever

Chikungunya Viral Disease

Chikungunya Mosquito-Borne Viral Fever
Mouth Disease

Mouth Diseases

Mouth Disorders
Avian Influenza

Bird Flu

Influenza In Birds

Avian Flu
Ebola Hemorrhagic Fever

Ebola Virus Disease

Viral Hemorrhagic Fever

Hemorrhagic Fever, Ebola

Ebola

Ehf

Ebola Fever

Hemorrhagic Fevers, Viral

Ebola Haemorrhagic Fever

Ebod - [Ebola Disease]

Evd - [Ebola Virus Disease]

Ebola Virus Haemorrhagic Fever

Vhf - [Viral Haemorrhagic Fever] Nos

Viral Haemorrhagic Fever, Not Otherwise Specified
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06568 IFITM3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus IFITM3 MGD MGI:1913391
Rattus norvegicus IFITM3 RGD RGD:1595844
Others IFITM3 NCBI
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