1. Gene
  2. HNRNPUL1 - heterogeneous nuclear ribonucleoprotein U like 1 Gene

HNRNPUL1 - heterogeneous nuclear ribonucleoprotein U like 1 Gene

中文名称:异质核核糖核蛋白 U 样 1

种属: Homo sapiens

同用名: E1BAP5; E1B-AP5; HNRPUL1

基因 ID: 11100 | 基因类型: protein coding

关于 HNRNPUL1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,262,557-41,307,787 (from NCBI)

This gene has 21 transcripts (splice variants), 205 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 41.5), ovary (RPKM 40.7) and 25 other tissues.

功能概要

该基因编码异质核核糖核蛋白 (hnRNP) 家族的核 RNA 结合蛋白。该蛋白特异性结合腺病毒早期 1B-55kDa 癌蛋白。它可能在核质 RNA 转运中发挥重要作用,其功能受腺病毒感染细胞中的早期 1B-55kDa 调节。[RefSeq 提供,2016 年 3 月]

This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. [provided by RefSeq, Mar 2016]

HNRNPUL1 基因产物(5)

mRNA Protein Name
NM_001301016.3 NP_001287945.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform e
NM_001321208.2 NP_001308137.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
NM_001321211.2 NP_001308140.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
NM_007040.6 NP_008971.2 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform a
NM_144732.5 NP_653333.1 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform d
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
11513728 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
12489984 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
11513728 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

HNRNPUL1 蛋白结构

SAP

SAP: SAP domain (5 - 37)

SPRY

SPRY: SPRY domain (255 - 386)

AAA_33

AAA_33: AAA domain (424 - 568)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 856 a.a.
蛋白主名 其他名称

heterogeneous nuclear ribonucleoprotein U-like protein 1

E1B 55kDa associated protein 5

HNRNPUL1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra HNRNPUL1 Q9BUJ2 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 VPS37C Homo sapiens A5D8V6
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 VPS37C Homo sapiens A5D8V6
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 SF3B4 Homo sapiens Q15427
Y2H
22365833
Intra HNRNPUL1 Q9BUJ2 SF3B4 Homo sapiens Q15427
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 SF3B4 Homo sapiens Q15427
Y2H Array
25416956
Intra HNRNPUL1 Q9BUJ2 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Y2H Array
29892012
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 HNRNPF Homo sapiens P52597
Y2H
22365833
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Anti Bait CoIP
12489984
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Y2H
12489984
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Pull Down
12489984
Intra HNRNPUL1 Q9BUJ2 BRD7 Homo sapiens Q9NPI1
Fluorescence
12489984
Intra HNRNPUL1 Q9BUJ2 RBM4B Homo sapiens Q9BQ04
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 MAPK1IP1L Homo sapiens Q8NDC0
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 MAPK1IP1L Homo sapiens Q8NDC0
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
31515488
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
25416956
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H
21516116
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Array
29892012
Intra HNRNPUL1 Q9BUJ2 WWP2 Homo sapiens O00308
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 KLHDC7B Homo sapiens Q96G42
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 KLHDC7B Homo sapiens Q96G42
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Prey Pooling
25416956
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Validated Y2H
25416956
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Prey Pooling
32296183
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Array
25416956
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Array
32296183
Intra HNRNPUL1 Q9BUJ2 DZIP3 Homo sapiens Q86Y13
Y2H Array
29892012
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta HNRNPUL1 VGNC VGNC:73401
Bos taurus HNRNPUL1 VGNC VGNC:50035
Rattus norvegicus HNRNPUL1 RGD RGD:1307456
Mus musculus HNRNPUL1 MGD MGI:2443517
Felis catus HNRNPUL1 VGNC VGNC:62828
Canis familiaris HNRNPUL1 VGNC VGNC:53724