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  2. DZIP3 - DAZ interacting zinc finger protein 3 Gene

DZIP3 - DAZ interacting zinc finger protein 3 Gene

中文名称:DAZ 相互作用锌指蛋白 3

种属: Homo sapiens

同用名: UURF2; PPP1R66; hRUL138

基因 ID: 9666 | 基因类型: protein coding

关于 DZIP3

Cytogenetic location: 3q13.13 Genomic coordinates (GRCh38): 3:108,589,510-108,694,840 (from NCBI)

This gene has 6 transcripts (splice variants), 191 orthologues and 4 paralogues. Broad expression in testis (RPKM 21.6), brain (RPKM 12.1) and 21 other tissues.

功能概要

启用多种功能,包括磷酸酶结合活性;多聚泛素修饰依赖性蛋白结合活性;和泛素蛋白转移酶活性。参与蛋白质多聚泛素化。位于细胞质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables several functions, including Phosphatase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-protein transferase activity. Involved in protein polyubiquitination. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DZIP3 基因产物(1)

mRNA Protein Name
NM_014648.4 NP_055463.1 E3 ubiquitin-protein ligase DZIP3

DZIP3 蛋白结构

zf-RING_2

zf-RING_2: Ring finger domain (1147 - 1188)

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  • 1208 a.a.
蛋白主名 其他名称

E3 ubiquitin-protein ligase DZIP3

DAZ interacting protein 3, zinc finger

DZIP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra DZIP3 Q86Y13 HNRNPUL1 Homo sapiens Q9BUJ2
Validated Y2H
32296183
Intra DZIP3 Q86Y13 UBE2E2 Homo sapiens Q96LR5
Y2H Array
19549727
Intra DZIP3 Q86Y13 FBXO17 Homo sapiens Q96EF6
Validated Y2H
32296183
Intra DZIP3 Q86Y13 TIAL1 Homo sapiens Q01085
Anti Tag CoIP
28514442
Intra DZIP3 Q86Y13 TIAL1 Homo sapiens Q01085
Anti Tag CoIP
33961781
Intra DZIP3 Q86Y13 ARHGAP32 Homo sapiens A7KAX9
Y2H Array
25416956
Intra DZIP3 Q86Y13 ARHGAP32 Homo sapiens A7KAX9
Y2H Prey Pooling
25416956
Intra DZIP3 Q86Y13 AP1M1 Homo sapiens Q9BXS5
Y2H Prey Pooling
25416956
Intra DZIP3 Q86Y13 AP1M1 Homo sapiens Q9BXS5
Validated Y2H
25416956
Intra DZIP3 Q86Y13 AP1M1 Homo sapiens Q9BXS5
Y2H Array
25416956
Intra DZIP3 Q86Y13 ZCCHC10 Homo sapiens Q8TBK6
Validated Y2H
25416956
Intra DZIP3 Q86Y13 ZCCHC10 Homo sapiens Q8TBK6
Y2H Array
31515488
Intra DZIP3 Q86Y13 ZNF24 Homo sapiens P17028
Validated Y2H
25416956
Intra DZIP3 Q86Y13 ZNF24 Homo sapiens P17028
Y2H Array
31515488
Intra DZIP3 Q86Y13 RBM4B Homo sapiens Q9BQ04
Y2H Array
25416956
Intra DZIP3 Q86Y13 RBM4B Homo sapiens Q9BQ04
Validated Y2H
25416956
Intra DZIP3 Q86Y13 CEP63 Homo sapiens Q96MT8
Validated Y2H
25416956
Intra DZIP3 Q86Y13 CEP63 Homo sapiens Q96MT8
Y2H Array
25416956
Intra DZIP3 Q86Y13 TOLLIP Homo sapiens Q9H0E2
Anti Tag CoIP
21903422
Intra DZIP3 Q86Y13 GTF2H2C Homo sapiens Q6P1K8
Y2H Prey Pooling
25416956
Intra DZIP3 Q86Y13 ATXN1 Homo sapiens P54253
Y2H
16713569
Intra DZIP3 Q86Y13 ZNF765 Homo sapiens Q7L2R6
Y2H Prey Pooling
25416956
Intra DZIP3 Q86Y13 ZNF765 Homo sapiens Q7L2R6
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Felis catus DZIP3 VGNC VGNC:61693
Rattus norvegicus DZIP3 RGD RGD:1563278
Bos taurus DZIP3 VGNC VGNC:28285
Mus musculus DZIP3 MGD MGI:1917433
Macaca mulatta DZIP3 VGNC VGNC:72019
Canis familiaris DZIP3 VGNC VGNC:40163