1. Gene
  2. MAPK7 - mitogen-activated protein kinase 7 Gene

MAPK7 - mitogen-activated protein kinase 7 Gene

中文名称:丝裂原活化蛋白激酶 7

种属: Rattus norvegicus

同用名: Bmk1; Erk5; Prkm7

基因 ID: 114509 | 基因类型: protein coding

关于 MAPK7

Primary_assembly 10: 46,170,167-46,176,267 reverse strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 193 orthologues, 21 paralogues and is associated with 8 phenotypes. Biased expression in Lung (RPKM 3.3), Testes (RPKM 29.4) and 9 other tissues.

功能概要

该基因编码的蛋白可启动 ATP 结合活性和 MAP 激酶活性。参与 ERK5 级联和蛋白质自身磷酸化。位于核内。与人 MAPK7(丝裂原活化蛋白激酶 7)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables ATP binding activity and MAP kinase activity. Involved in ERK5 cascade and protein autophosphorylation. Located in nucleus. Orthologous to human MAPK7 (mitogen-activated protein kinase 7). [provided by Alliance of Genome Resources, Apr 2022]

MAPK7 基因产物(1)

mRNA Protein Name
NM_001191547.1 NP_001178476.1 mitogen-activated protein kinase 7
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
8663194 RGD
enables MAP kinase activity IDA
IDA: 通过直接分析推断
8663194 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19103177 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERK5 cascade IMP
IMP: 通过突变表型推断
11782488 RGD
involved in MAPK cascade IMP
IMP: 通过突变表型推断
11782488 RGD
involved in negative regulation of smooth muscle cell apoptotic process IMP
IMP: 通过突变表型推断
20724525 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
11782488 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
8663194 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MAPK7 蛋白结构

STKc_ERK5

STKc_ERK5: cd07855 (48 - 383)

  • 0
  • 200
  • 400
  • 600
  • 812 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase 7

BMK-1

BMK1 kinase

ERK-5

MAP kinase 7

MAPK 7

big MAP kinase 1

extracellular signal-regulated kinase 5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens MAPK7 NCBI NCBI:5598