2. Gene
  3. VASN - vasorin Gene

VASN - vasorin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：血管素

种属: Homo sapiens

同用名: SLITL2

基因 ID: 114990 | 基因类型: protein coding

关于 VASN

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:4,371,848-4,383,538 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 255 orthologues and 22 paralogues. Broad expression in placenta (RPKM 16.9), kidney (RPKM 16.4) and 24 other tissues.

功能概要

启用转化生长因子 β 结合活性。参与上皮间充质转化的负调控和转化生长因子β受体信号通路的负调控。位于细胞表面和细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Enables transforming growth factor beta binding activity. Involved in negative regulation of epithelial to mesenchymal transition and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cell surface and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

VASN 基因产物(1)

mRNA Protein Name
NM_138440.3 NP_612449.2 vasorin precursor

VASN 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (23 - 51)

LRR_1

LRR_1: Leucine Rich Repeat (78 - 98)

LRR_8

LRR_8: Leucine rich repeat (101 - 160)

LRR_8

LRR_8: Leucine rich repeat (193 - 249)

  • 0
  • 200
  • 400
  • 600
  • 673 a.a.
蛋白主名 其他名称

vasorin

protein slit-like 2

重组 VASN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70999 Vasorin Protein, Human (552a.a, HEK293, His) Q6EMK4/AAH68575.1 (C24-P575) ≥95%

关联疾病

疾病名称 别名
Hematuria, Benign Familial

Benign Familial Hematuria

BFH

Thin Membrane Nephropathy

Tmn

Thin Basement Membrane Nephropathy

Thin-Basement-Membrane Nephropathy

Hematuria, Familial Benign

Hematuria Benign Familial

Hematuria, Benign, Familial

Thin Basement Membrane Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15608 VASN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus VASN MGD MGI:2177651
Canis familiaris VASN VGNC VGNC:54089
Rattus norvegicus VASN RGD RGD:1598149
Felis catus VASN VGNC VGNC:66921
Others VASN NCBI
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