Il13 - interleukin 13 Gene

中文名称：白细胞介素 13

种属: Rattus norvegicus

关于 Il13

功能概要

该基因编码的蛋白可启动白细胞介素 13 受体结合活性。参与多个过程，包括细胞群增殖的正向调节；大分子代谢过程的正向调控；和调节阳离子跨膜运输。位于细胞外空间。用于研究哮喘；外源性过敏性肺泡炎;和类脂性肾病。几种疾病的生物标志物，包括酒精性肝炎；大脑中动脉梗塞;消化性食管炎;前列腺肥大;和肺纤维化。该基因的人类直系同源物与多种疾病有关，包括过敏性疾病（多种）；自身免疫性疾病（多种）；弥漫性硬皮病;肺部疾病（多发）；和鼻子疾病（多种）。与人 IL13（白细胞介素 13）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables interleukin-13 receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of macromolecule metabolic process; and regulation of cation transmembrane transport. Located in extracellular space. Used to study asthma; extrinsic allergic alveolitis; and lipoid nephrosis. Biomarker of several diseases, including alcoholic hepatitis; middle cerebral artery infarction; peptic esophagitis; prostatic hypertrophy; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13). [provided by Alliance of Genome Resources, Apr 2022]