Bcl2l2 - BCL2-like 2 Gene

中文名称：BCL2 样2

种属: Mus musculus

同用名: c98; bclw; Bcl-w; Gtrgal2; Gtrosa41

关于 Bcl2l2

功能概要

预测该基因编码的蛋白可实现蛋白质二聚化活性和蛋白质结构域特异性结合活性。在没有配体的情况下，作用于支持细胞增殖和外在凋亡信号通路的上游或内部。位于胞质溶胶和线粒体膜中。以多种结构表达，包括中枢神经系统；早孕;胆囊;泌尿生殖系统；和肠道。该基因的人类直系同源物与短暂性脑缺血有关。与人类 BCL2L2 同源（BCL2 like 2）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein dimerization activity and protein domain specific binding activity. Acts upstream of or within Sertoli cell proliferation and extrinsic apoptotic signaling pathway in absence of ligand. Located in cytosol and mitochondrial membrane. Is expressed in several structures, including central nervous system; early conceptus; gallbladder; genitourinary system; and intestine. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human BCL2L2 (BCL2 like 2). [provided by Alliance of Genome Resources, Apr 2022]