2. Gene
  3. Bcar1 - breast cancer anti-estrogen resistance 1 Gene

Bcar1 - breast cancer anti-estrogen resistance 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cas; Crkas

基因 ID: 12927 | 基因类型: protein coding

关于 Bcar1

功能概要

Predicted to enable protein domain specific binding activity and protein kinase binding activity. Involved in G protein-coupled receptor signaling pathway and platelet-derived growth factor receptor signaling pathway. Acts upstream of or within cell migration. Located in several cellular components, including actin cytoskeleton; focal adhesion; and lamellipodium. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to human BCAR1 (BCAR1 scaffold protein, Cas family member). [provided by Alliance of Genome Resources, Apr 2022]

Bcar1 基因产物(2)

mRNA Protein Name
NM_001198839.1 NP_001185768.1 breast cancer anti-estrogen resistance protein 1 isoform A
NM_009954.3 NP_034084.2 breast cancer anti-estrogen resistance protein 1 isoform B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
7479864 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
9083073 MGI
acts upstream of or within cell migration IDA
IDA: 通过直接分析推断
15728191 MGI
involved in platelet-derived growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
9083073 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
11864995 MGI
located in focal adhesion IDA
IDA: 通过直接分析推断
15728191 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
15728191 MGI
located in membrane IMP
IMP: 通过突变表型推断
22801373 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

breast cancer anti-estrogen resistance protein 1

CRK-associated substrate

p130 Cas

p130cas

v-crk-associated tyrosine kinase substrate

Bcar1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Bcar1 Q61140 Ptk2 Mus musculus P34152
Anti Bait CoIP
18233957
种属内
Bcar1 Q61140 Nphp1 Mus musculus Q9QY53
Y2H
10739664
种属内
Bcar1 Q61140 Srcin1 Mus musculus Q9QWI6
Pull Down
14657239
种属间
Bcar1 Q61140 PTPN1 Homo sapiens P18031
Phosphatase Assay
9418872
种属间
Bcar1 Q61140 PTPN1 Homo sapiens P18031
Pull Down
12023880
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01397 BCAR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bcar1 NCBI NCBI:9564
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