1. Gene
  2. Dnase1l3 - deoxyribonuclease 1-like 3 Gene

Dnase1l3 - deoxyribonuclease 1-like 3 Gene

种属: Mus musculus

同用名: Lsd; Dhp2; DNasegamma

基因 ID: 13421 | 基因类型: protein coding

关于 Dnase1l3

功能概要

Enables Endonuclease activity. Involved in several processes, including DNA catabolic process, endonucleolytic; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Acts upstream of or within apoptotic DNA fragmentation and programmed cell death involved in cell development. Located in nucleus. Orthologous to human DNASE1L3 (deoxyribonuclease 1 like 3). [provided by Alliance of Genome Resources, Apr 2022]

Dnase1l3 基因产物(1)

mRNA Protein Name
NM_007870.3 NP_031896.3 deoxyribonuclease gamma precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables endonuclease activity IDA
IDA: 通过直接分析推断
12050166 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA catabolic process IDA
IDA: 通过直接分析推断
29191910 MGI
acts upstream of or within apoptotic DNA fragmentation IDA
IDA: 通过直接分析推断
12050166 MGI
involved in neutrophil activation involved in immune response IDA
IDA: 通过直接分析推断
29191910 MGI
acts upstream of or within programmed cell death involved in cell development IDA
IDA: 通过直接分析推断
12050166 MGI
involved in regulation of acute inflammatory response IDA
IDA: 通过直接分析推断
29191910 MGI
involved in regulation of neutrophil mediated cytotoxicity IDA
IDA: 通过直接分析推断
29191910 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12050166 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

deoxyribonuclease gamma

DNase I homolog protein DHP2

DNase I-like 3

DNase gamma

LS-DNase

deoxyribonuclease I-like 3

liver and spleen DNase

macrophage specific DNase I

重组 Dnase1l3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P790035 DNase1L3 Protein, Mouse (His) O55070 (L26-S310) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dnase1l3 NCBI NCBI:1776