Prmt1 - protein arginine N-methyltransferase 1 Gene

中文名称：蛋白精氨酸 N-甲基转移酶 1

种属: Mus musculus

同用名: Mrmt1; Hrmt1l2; 6720434D09Rik

关于 Prmt1

功能概要

该基因编码的蛋白可启动组蛋白甲基转移酶活性和蛋白质-精氨酸 omega-N 不对称甲基转移酶活性。参与 RNA 剪接和心肌组织发育。作用于子宫内胚胎发育和肽基-精氨酸甲基化的上游或内部，形成不对称-二甲基精氨酸。位于核内。以多种结构表达，包括消化系统；鳃弓;中枢神经系统;泌尿生殖系统；和肺。与人类 PRMT1（蛋白质精氨酸甲基转移酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Histone Methyltransferase activity and protein-arginine omega-N asymmetric methyltransferase activity. Involved in RNA splicing and cardiac muscle tissue development. Acts upstream of or within in utero embryonic development and peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and lung. Orthologous to human PRMT1 (protein arginine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]