1. Gene
  2. Hspd1 - heat shock protein 1 (chaperonin) Gene

Hspd1 - heat shock protein 1 (chaperonin) Gene

种属: Mus musculus

同用名: 60kDa; CPN60; Hsp60; HSP-60; HSP-65

基因 ID: 15510 | 基因类型: protein coding

关于 Hspd1

功能概要

Enables lipopolysaccharide binding activity. Involved in positive regulation of T cell activation. Acts upstream of or within T cell activation; cellular response to interleukin-7; and positive regulation of cytokine production. Located in mitochondrion; plasma membrane; and secretory granule. Is expressed in several structures, including brain; eye; and urinary system. Used to study hereditary spastic paraplegia 13. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Orthologous to human HSPD1 (heat shock protein family D (Hsp60) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hspd1 基因产物(2)

mRNA Protein Name
NM_001356512.1 NP_001343441.1 60 kDa heat shock protein, mitochondrial
NM_010477.4 NP_034607.3 60 kDa heat shock protein, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipopolysaccharide binding IDA
IDA: 通过直接分析推断
17164250 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
21874024 MGI
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
15136728 MGI
located in membrane IMP
IMP: 通过突变表型推断
20080761 MGI
located in migrasome IDA
IDA: 通过直接分析推断
34048705 MGI
is active in mitochondrion IDA
IDA: 通过直接分析推断
26644517 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
1516759 MGI
located in secretory granule IDA
IDA: 通过直接分析推断
1516759 MGI
located in sperm plasma membrane IDA
IDA: 通过直接分析推断
15252132 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

60 kDa heat shock protein, mitochondrial

60 kDa chaperonin

chaperonin 60

heat shock 60kDa protein 1 (chaperonin)

heat shock protein 60

heat shock protein, 60 kDa

mitochondrial matrix protein P1

重组 Hspd1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73916 HSP60 Protein, Mouse (His, solution) P63038 (L2-F573) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspd1 NCBI NCBI:3329