2. Gene
  3. Nectin2 - nectin cell adhesion molecule 2 Gene

Nectin2 - nectin cell adhesion molecule 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MPH; Pvr; Pvs; Cd112; Pvrl2; nectin-2

基因 ID: 19294 | 基因类型: protein coding

关于 Nectin2

功能概要

Enables cell adhesion molecule binding activity and protein homodimerization activity. Involved in homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within several processes, including establishment of mitochondrion localization; sperm mitochondrion organization; and spermatid development. Located in cell-cell contact zone; plasma membrane; and zonula adherens. Is expressed in brain; cochlea; enamel organ; male reproductive system; and primitive collecting duct. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human NECTIN2 (nectin cell adhesion molecule 2). [provided by Alliance of Genome Resources, Apr 2022]

Nectin2 基因产物(2)

mRNA Protein Name
NM_001159724.1 NP_001153196.1 nectin-2 isoform 2 precursor
NM_008990.3 NP_033016.3 nectin-2 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion molecule binding IPI
IPI: 通过物理相互作用推断
10225955 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
22902367 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12759359 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
12826663 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within acrosome assembly IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within cellular anatomical entity morphogenesis IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within cilium organization IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within cytoskeleton organization IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within establishment of mitochondrion localization IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within fertilization IMP
IMP: 通过突变表型推断
10733589 MGI
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
acts upstream of or within sperm mitochondrion organization IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
10733589 MGI
involved in spermatid development IMP
IMP: 通过突变表型推断
10733589 MGI
acts upstream of or within spermatid nucleus differentiation IMP
IMP: 通过突变表型推断
10733589 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical junction complex IDA
IDA: 通过直接分析推断
22512338 MGI
located in cell-cell contact zone IDA
IDA: 通过直接分析推断
23533177 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
15660130 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12826663 MGI
located in zonula adherens IDA
IDA: 通过直接分析推断
10225955 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nectin-2

herpes virus entry mediator B

herpesvirus entry mediator B

hveB

mHveB

murine herpes virus entry protein B

murine herpesvirus entry protein B

poliovirus receptor homolog

poliovirus receptor-related 2

poliovirus receptor-related protein 2

polioviru

重组 Nectin2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7781 Nectin-2/CD112 Protein, Mouse (HEK293, His) P32507 (Q32-G351) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09175 NECTIN2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nectin2 NCBI NCBI:5819
Macaca fascicularis Nectin2 NCBI NCBI:102137456
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