2. Gene
  3. Sema5a - sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A Gene

Sema5a - sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: semF; Semaf; 5930434A13; 9130201M22Rik

基因 ID: 20356 | 基因类型: protein coding

关于 Sema5a

功能概要

Enables axon guidance receptor activity and semaphorin receptor binding activity. Involved in several processes, including blood vessel endothelial cell proliferation involved in sprouting angiogenesis; negative regulation of endothelial cell apoptotic process; and regulation of signal transduction. Acts upstream of or within axonogenesis; branching involved in blood vessel morphogenesis; and detection of light stimulus involved in visual perception. Is integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human SEMA5A (semaphorin 5A). [provided by Alliance of Genome Resources, Apr 2022]

Sema5a 基因产物(1)

mRNA Protein Name
NM_009154.2 NP_033180.2 semaphorin-5A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables axon guidance receptor activity IDA
IDA: 通过直接分析推断
12506007 MGI
enables semaphorin receptor binding IPI
IPI: 通过物理相互作用推断
15218527 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon extension IGI
IGI: 通过遗传相互作用推断
21835343 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
12506007 MGI
involved in blood vessel endothelial cell proliferation involved in sprouting angiogenesis IDA
IDA: 通过直接分析推断
19850054 MGI
acts upstream of or within branching involved in blood vessel morphogenesis IMP
IMP: 通过突变表型推断
15743826 MGI
acts upstream of or within branching morphogenesis of an epithelial tube IMP
IMP: 通过突变表型推断
15743826 MGI
involved in cell chemotaxis IDA
IDA: 通过直接分析推断
15218527 MGI
acts upstream of or within detection of light stimulus involved in visual perception IGI
IGI: 通过遗传相互作用推断
21835343 MGI
involved in negative regulation of cell adhesion IDA
IDA: 通过直接分析推断
15218527 MGI
involved in negative regulation of endothelial cell apoptotic process IDA
IDA: 通过直接分析推断
19850054 MGI
acts upstream of or within neuron projection extension IDA
IDA: 通过直接分析推断
21835343 MGI
acts upstream of or within neuron projection extension IGI
IGI: 通过遗传相互作用推断
21835343 MGI
acts upstream of or within neuron projection guidance IGI
IGI: 通过遗传相互作用推断
21835343 MGI
involved in positive chemotaxis IDA
IDA: 通过直接分析推断
15218527 MGI
involved in positive regulation of actin filament depolymerization IDA
IDA: 通过直接分析推断
19850054 MGI
involved in positive regulation of angiogenesis IDA
IDA: 通过直接分析推断
19850054 MGI
involved in positive regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
19850054 MGI
involved in positive regulation of endothelial cell chemotaxis IDA
IDA: 通过直接分析推断
19850054 MGI
involved in positive regulation of endothelial cell proliferation IDA
IDA: 通过直接分析推断
19850054 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
19850054 MGI
involved in semaphorin-plexin signaling pathway IDA
IDA: 通过直接分析推断
15218527 MGI
involved in signal clustering IDA
IDA: 通过直接分析推断
15218527 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
12506007 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

semaphorin-5A

M-Sema D

sema F

semaphorin F

重组 Sema5a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74559 Semaphorin-5A/SEMA5A Protein, Mouse (HEK293, His) Q3UPZ0 (E23-T765) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12663 SEMA5A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sema5a NCBI NCBI:9037
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