JMJD6 - jumonji domain containing 6, arginine demethylase and lysine hydroxylase Gene

中文名称：含 Jumonji 结构域 6，精氨酸脱甲基酶和赖氨酸羟化酶

种属: Homo sapiens

同用名: PSR; PTDSR; PTDSR1

关于 JMJD6

功能概要

该基因编码具有 JmjC 结构域的核蛋白。预测含有 JmjC 结构域的蛋白质起蛋白质羟化酶或组蛋白去甲基化酶的作用。该蛋白首先被鉴定为参与凋亡细胞吞噬作用的假定磷脂酰丝氨酸受体；然而，随后的研究表明它并不直接在凋亡细胞的清除中发挥作用，并质疑它是否是真正的磷脂酰丝氨酸受体。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]