1. Gene
  2. Thy1 - Thy-1 cell surface antigen Gene

Thy1 - Thy-1 cell surface antigen Gene

种属: Rattus norvegicus

同用名: CD7

基因 ID: 24832 | 基因类型: protein coding

关于 Thy1

功能概要

Enables GPI anchor binding activity; GTPase activator activity; and protein kinase binding activity. Involved in several processes, including T cell receptor signaling pathway; focal adhesion assembly; and negative regulation of neuron projection development. Located in several cellular components, including growth cone; neuron projection membrane; and neuronal cell body membrane. Is anchored component of plasma membrane. Biomarker of retinal disease and retinal ischemia. Orthologous to human THY1 (Thy-1 cell surface antigen). [provided by Alliance of Genome Resources, Apr 2022]

Thy1 基因产物(1)

mRNA Protein Name
NM_012673.2 NP_036805.1 thy-1 membrane glycoprotein preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GPI anchor binding IDA
IDA: 通过直接分析推断
16257296 RGD
enables GTPase activator activity IDA
IDA: 通过直接分析推断
15093746 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
8666426 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10814697 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
8870703 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell receptor signaling pathway IMP
IMP: 通过突变表型推断
9285719 RGD
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
9285719 RGD
acts upstream of or within positive effect cell-cell signaling IDA
IDA: 通过直接分析推断
22479590 RGD
involved in cytoskeleton organization IDA
IDA: 通过直接分析推断
15093746 RGD
involved in focal adhesion assembly IDA
IDA: 通过直接分析推断
15093746 RGD
involved in negative regulation of axonogenesis IDA
IDA: 通过直接分析推断
15547945 RGD
involved in negative regulation of cell migration IDA
IDA: 通过直接分析推断
15093746 RGD
acts upstream of or within positive effect negative regulation of neuron projection regeneration IMP
IMP: 通过突变表型推断
22479590 RGD
involved in negative regulation of protein kinase activity IDA
IDA: 通过直接分析推断
15093746 RGD
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
15093746 RGD
involved in positive regulation of T cell activation IDA
IDA: 通过直接分析推断
7722293 RGD
involved in positive regulation of release of sequestered calcium ion into cytosol IDA
IDA: 通过直接分析推断
2873512 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
19723805 RGD
involved in receptor clustering IDA
IDA: 通过直接分析推断
22479590 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
20187850 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axolemma IDA
IDA: 通过直接分析推断
22479590 RGD
located in cell surface IDA
IDA: 通过直接分析推断
15474526 RGD
located in cytosol IDA
IDA: 通过直接分析推断
15547945 RGD
located in dendrite membrane IDA
IDA: 通过直接分析推断
22479590 RGD
located in growth cone IDA
IDA: 通过直接分析推断
10601014 RGD
located in membrane raft IDA
IDA: 通过直接分析推断
14499952 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
22479590 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
15547945 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

thy-1 membrane glycoprotein

CD90

Thy-1 protein

Thymus cell surface antigen

thy-1 antigen

thy-1 glycoprotein

thymus cell antigen 1, theta

重组 Thy1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74514 Thy1/CD90 Protein, Rat (HEK293, His) P01830 (Q20-K129) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Thy1 NCBI NCBI:7070
Macaca fascicularis Thy1 NCBI NCBI:102139037
Mus musculus Thy1 NCBI NCBI:21838